Document Detail

Effects of lifestyle measures, antiobesity agents, and bariatric surgery on serological markers of inflammation in obese patients.
MedLine Citation:
PMID:  20224654     Owner:  NLM     Status:  MEDLINE    
Overweight and obesity are highly prevalent in developed countries and are also becoming more frequent in the developing world. Overweight and obese patients have elevated levels of several inflammatory markers and this inflammatory state might contribute to their increased vascular risk. We summarize the effects of lifestyle changes, antiobesity agents, and bariatric surgery on serological inflammatory markers in overweight and obese patients. Most studies showed a decrease in inflammation with all 3 interventions. However, it remains to be established whether the decrease in inflammatory markers induced by lifestyle changes or (where indicated) with antiobesity agents or bariatric surgery will translate into reduced vascular morbidity and mortality in overweight and obese patients.
Konstantinos Tziomalos; Hariklia V Dimitroula; Niki Katsiki; Christos Savopoulos; Apostolos I Hatzitolios
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-03-07
Journal Detail:
Title:  Mediators of inflammation     Volume:  2010     ISSN:  1466-1861     ISO Abbreviation:  Mediators Inflamm.     Publication Date:  2010  
Date Detail:
Created Date:  2010-03-12     Completed Date:  2010-05-31     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  9209001     Medline TA:  Mediators Inflamm     Country:  United States    
Other Details:
Languages:  eng     Pagination:  364957     Citation Subset:  IM    
First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, 54646, Thessaloniki, Greece.
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MeSH Terms
Anti-Obesity Agents / therapeutic use*
Bariatric Surgery*
Biological Markers / metabolism*
Inflammation / blood*
Life Style*
Obesity* / blood,  immunology,  therapy
Reg. No./Substance:
0/Anti-Obesity Agents; 0/Biological Markers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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