Document Detail


Effects of lactose and yeast-dried milk on growth performance, fecal microbiota, and immune parameters of nursery pigs.
MedLine Citation:
PMID:  22266995     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
An experiment was conducted to evaluate the effects of dietary lactose alone or in combination with a yeast-dried milk product (50% dried near-dated milk; 50% dried yeast) on growth performance, fecal microbiota, and immune status in nursery pigs. A total of 108 pigs (age, 20 ± 1 d; initial BW, 6.07 ± 0.03 kg) were randomly allotted to 18 pens (6 pigs/pen; 6 pens/treatment). Dietary treatments were: 1) control, 2) control + lactose, and 3) control + lactose + 5% yeast-dried milk. Except for the control diet, diets in Phase 1 (wk 1 and 2), 2 (wk 3 and 4), and 3 (wk 5) contained 20, 15, and 5% total lactose, respectively. Blood samples were collected from all pigs at d 0, 14, 28, and 35 to determine circulating IgG, IgA, and tumor necrosis factor (TNF)-α concentrations. At d 0, 7, and 14, fecal samples were collected (n = 18; 6 pigs/treatment) to evaluate fecal microbiota using PCR-denaturing gradient gel electrophoresis. Compared to pigs fed the control diet, pigs fed lactose and lactose with yeast-dried milk had greater (P < 0.05) ADG and tended (P = 0.07) to have greater BW and ADFI during Phase 1. There were no differences for BW, ADG, or ADFI during Phase 2, 3, or the overall experimental period. A main effect of treatment was observed for circulating IgA where control pigs had greater (P < 0.01) IgA compared to pigs fed lactose with or without yeast-dried milk; however, no effects of treatment were observed for circulating IgG or TNF-α. No differences in microbial diversity indices were observed on d 7 or 14 among treatments. However, a shift in microbial composition was observed on d 7 with lactose-fed pigs having greater (P < 0.05) putative L. johnsonii staining intensity compared to control pigs and pigs fed lactose plus yeast-dried milk. On d 14, L. reuteri tended (P = 0.15) to be enhanced, and L. delbrueckii was eliminated (P < 0.04) by feeding lactose with or without yeast-dried milk. This research indicates that growth performance, immune status, and fecal microbiota are affected by dietary inclusion of lactose alone, or in combination with yeast-dried milk.
Authors:
H Tran; R Moreno; E E Hinkle; J W Bundy; J Walter; T E Burkey; P S Miller
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-20
Journal Detail:
Title:  Journal of animal science     Volume:  -     ISSN:  1525-3163     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003002     Medline TA:  J Anim Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Animal Science, University of Nebraska, Lincoln 68583.
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