| Effects of kainic acid on synaptic transmission in electroreceptors (the ampullae of Lorenzini) of skates. | |
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MedLine Citation:
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PMID: 2889576 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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1. Effects of kainic acid (KA) on resting and evoked activities of the ampullary electroreceptor were studied in marine skates (Raja clavata). 2. Perfusion of the basal membrane with 10(-6)-10(-9) M KA produced significant and reversible changes in impulse activity depending on initial firing rate. 3. When synaptic transmission was blocked by perfusion with elevated Mg2+, the resting and evoked activities were restored if KA was added. 4. The results are consistent with the view that KA is a potent excitant of the ampullae receptors and its effects appear to be presynaptic. |
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Authors:
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G N Akoev; G N Andrianov; T Szabo |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Comparative biochemistry and physiology. A, Comparative physiology Volume: 88 ISSN: 0300-9629 ISO Abbreviation: Comp Biochem Physiol A Comp Physiol Publication Date: 1987 |
Date Detail:
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Created Date: 1987-12-17 Completed Date: 1987-12-17 Revised Date: 2008-10-30 |
Medline Journal Info:
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Nlm Unique ID: 1276312 Medline TA: Comp Biochem Physiol A Comp Physiol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 61-3 Citation Subset: IM; S |
Affiliation:
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Pavlov Institute of Physiology, Academy of Sciences of the USSR, Leningrad. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Electric Conductivity Electric Fish / physiology* Evoked Potentials / drug effects Kainic Acid / pharmacology* Magnesium / pharmacology Mechanoreceptors / drug effects, physiology* Membrane Potentials / drug effects Skates (Fish) / physiology* Synapses / drug effects, physiology* Synaptic Transmission / drug effects* |
| Chemical | |
Reg. No./Substance:
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487-79-6/Kainic Acid; 7439-95-4/Magnesium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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