| Effects of isometric handgrip training on blood pressure (resting and 24 h ambulatory) and heart rate variability in medicated hypertensive patients. | |
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MedLine Citation:
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PMID: 22322195 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVES: Isometric handgrip (IHG) training (four, 2-min sustained contractions at 30% of maximal voluntary contraction, three times per week for 8-10 weeks) lowers resting arterial blood pressure (BP) in hypertensive patients, including those receiving pharmacotherapy, although the mechanisms remain elusive. Ambulatory BP measurements are more efficacious in predicting cardiovascular disease-related events, yet the effects of IHG training on ambulatory BP are unknown. The objective of the current investigation was to test the hypotheses that 8 weeks of IHG training lowers resting and 24 h ambulatory BP concomitantly in medicated hypertensive patients, and may be the result of improved vagal modulation. METHODS: BP was assessed using brachial artery oscillometry, and coarse-graining spectral analysis was used to determine spectral power. Resting and 24 h ambulatory BP and heart rate variability (HRV) were measured pretraining, midtraining, and post-training in 11 medicated hypertensive patients (mean±SD, resting BP: 113.9±12.7/60.7±11.6 mmHg), and in nine medicated hypertensive controls (resting BP: 117.8±14.3/67.5±4.2 mmHg). RESULTS: Indices of BP and HRV were not significantly altered with IHG training (all P>0.05). CONCLUSION: IHG training does not lower resting or ambulatory BP in hypertensive patients successfully treated with pharmacotherapy to within the normal range (≤120/80 mmHg), nor does it improve HRV. Future studies should examine alternative IHG training protocols in well-managed hypertensive patients and/or target poorly controlled medicated hypertensive patients. |
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Authors:
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Cassandra Stiller-Moldovan; Kenji Kenno; Cheri L McGowan |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-2-9 |
Journal Detail:
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Title: Blood pressure monitoring Volume: - ISSN: 1473-5725 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-2-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9606438 Medline TA: Blood Press Monit Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Kinesiology, University of Windsor, Windsor, Ontario, Canada. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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