Document Detail

Effects of "isolating hemodialysis" on prevention of methicillin-resistant Staphylococcus aureus cross-infection in a hemodialysis unit.
MedLine Citation:
PMID:  10968688     Owner:  NLM     Status:  MEDLINE    
AIM: To evaluate the effects of a contact isolation program against methicillin-resistant Staphylococcus aureus (MRSA) cross-infection among patients in a hemodialysis unit. CLINICAL SETTING AND METHODS: In all patients maintaining hemodialysis therapy were tested for MRSA infection and who had MRSA infection, not only inpatients but also outpatients were separated into a designated area (isolating hemodialysis). Clinically isolated MRSA strains were clonotyped with coagulase typing, staphylococcal enterotoxin typing and restriction enzyme analysis of plasmid DNA. RESULTS: The frequency of patients with MRSA infection was 4.5% before starting this protocol and was reduced to 2.9% two and a half years later. At this time, MRSA was isolated from the 8 patients. These 8 clinical strains were differentiated into 6 clonotypes and 3 strains showed the same patterns. Two of 3 were isolated from inpatients and the other was from a patient with community onset MRSA colitis. In this case, most MRSA infections were independent under prophylaxis control and cross-infection was observed only once between hospitalized patients who stayed in a same ward. CONCLUSION: This "isolating hemodialysis" should be useful to prevent cross-infection among patients in end-stage renal disease in a dialysis unit.
E Osono; M Takahashi; S Kurihara; K Ohwada; Y Sakurai; N Onoda; M Takeuchi; H Yoneshima; N Hayama; Y Iino; M Saji; R Shikita; H Takahashi; H Ohkuni
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical nephrology     Volume:  54     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2000-12-27     Completed Date:  2000-12-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  128-33     Citation Subset:  IM    
Department of Nephrology, Kasukabe Shuwa Hospital, Saitama, Japan.
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MeSH Terms
Cross Infection / prevention & control*
Hemodialysis Units, Hospital*
Infection Control / methods*
Methicillin Resistance
Middle Aged
Renal Dialysis
Staphylococcal Infections / prevention & control*
Staphylococcus aureus / classification,  isolation & purification
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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