| Effects of ischemia on repolarization in patients with single and multivessel coronary disease. | |
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MedLine Citation:
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PMID: 12687852 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To evaluate if QT dispersion (QTd) may be affected by the number of obstructed coronary arteries (CAs) in patients with acute myocardial infarction (MI) and undergoing angioplasty, and to evaluate if QTd may be affected by ejection function of the heart. The infarct related CA was identified by coronary angiography in 141 patients (97 men, mean age 61.6 +/- 12.9 years) with acute MI undergoing percutaneous angioplasty. Successful reperfusion was defined as TIMI III flow with < 20% residual stenosis. QTd, calculated by subtracting the shortest from the longest QT interval on 12-lead electrocardiograms, was examined immediately before and after angioplasty, at 24 hours, and 3 days after angioplasty. Successful reperfusion was achieved in 98 (69.5%) patients. Prolonged QTd at baseline was found in all patients with ischemia. A trend toward a decrease in QTd was observed immediately after angioplasty and at 24 hours, and a significant decrease at 3 days in patients with successful reperfusion regardless of the number of occluded CAs. There was no change in QTd found in patients with no reperfusion. An increase in QTd was observed in patients with acute ischemia due to single or multivessel disease. |
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Authors:
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Dalia Giedrimiene; Satyendra Giri; Arnoldas Giedrimas; Frank Kiernan; Jeffrey Kluger |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pacing and clinical electrophysiology : PACE Volume: 26 ISSN: 0147-8389 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 2003 Jan |
Date Detail:
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Created Date: 2003-04-11 Completed Date: 2003-07-03 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: United States |
Other Details:
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Languages: eng Pagination: 390-3 Citation Subset: IM |
Affiliation:
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Hartford Hospital Division of Cardiology, Hartford, Saint Joseph College, Department of Biology, West Hartford, Connecticut, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Transluminal, Percutaneous Coronary Coronary Vessels / pathology Electrocardiography* Female Humans Male Middle Aged Myocardial Infarction / complications, pathology, physiopathology*, therapy Myocardial Ischemia / complications, physiopathology* Myocardial Reperfusion Stroke Volume Ventricular Function |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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