| Effects of ischemia on P wave dispersion and maximum P wave duration during spontaneous anginal episodes. | |
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MedLine Citation:
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PMID: 10598968 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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P wave dispersion (P dispersion), defined as the difference between the maximum and the minimum P wave duration, and maximum P wave duration (P maximum) are electrocardiographic (ECG) markers that have been used to evaluate the discontinuous propagation of sinus impulses and the prolongation of atrial conduction time, respectively. To study the effects of myocardial ischemia on P dispersion and P maximum, 95 patients with coronary artery disease (CAD) and typical angina pectoris and 15 controls with angina like symptoms underwent 12-lead surface ECG during and after the relief of pain. During pain and during the asymptomatic period, P maximum and P dispersion were calculated from the averaged complexes of all 12 leads. P dispersion increased significantly during spontaneous angina (45+/-17 ms) compared to the asymptomatic period (40+/-15 ms), P < 0.001 only in the patient group. Both P maximum and P dispersion showed higher values during angina in those patients who developed diffuse ischemia, as estimated with ST segment changes in multiple ECG leads. P dispersion showed higher values during the anginal episode in patients with left ventricular dysfunction, independently of the presence of a previous myocardial infarction. Atrial conduction abnormalities, as estimated with P maximum and particularly P dispersion, are significantly influenced by myocardial ischemia in patients with CAD and spontaneous angina. |
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Authors:
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P E Dilaveris; G K Andrikopoulos; G Metaxas; D J Richter; C K Avgeropoulou; A M Androulakis; E J Gialafos; A P Michaelides; P K Toutouzas; J E Gialafos |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Pacing and clinical electrophysiology : PACE Volume: 22 ISSN: 0147-8389 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 1999 Nov |
Date Detail:
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Created Date: 2000-01-28 Completed Date: 2000-01-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1640-7 Citation Subset: IM |
Affiliation:
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State Department of Cardiology, Hippokration Hospital, Athens, Greece. hrodil@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Angina Pectoris / diagnosis, physiopathology* Atrioventricular Node / physiopathology Electrocardiography* Female Heart Atria / physiopathology Heart Ventricles / physiopathology Humans Male Middle Aged Myocardial Infarction / diagnosis, physiopathology Myocardial Ischemia / diagnosis, physiopathology* Recurrence Sinoatrial Node / physiopathology Ventricular Dysfunction, Left / diagnosis, physiopathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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