| Effects of intravenous administration of dexmedetomidine on intraocular pressure and pupil size in clinically normal dogs. | |
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MedLine Citation:
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PMID: 22050915 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objective To evaluate the effects of the intravenous administration of dexmedetomidine on the intraocular pressure (IOP) and pupil size (PS) in normal dogs. Animals studied Forty-two animals with no ocular abnormalities were included in this study. Procedure Following initial readings (T(0) ) of IOP and PS, the dogs received an intravenous injection of dexmedetomidine (5 μg/kg). Both measurements were repeated 10 min (T(10) ) and 20 min (T(20) ) later. Results There were no significant differences in IOP measurements between T(0) and T(10) , although a significant decrease was observed at T(20) . A significant miosis was found in the first 10 min after sedation. At T(20) , the PS slightly increased, resulting in no statistical differences with T(0) and T(10) . Conclusion Dexmedetomidine is an excellent option for surgery or diagnostic ocular procedures in dogs when a specific control of IOP is required. However, it must be used in combination with mydriatics in ophthalmic surgical or diagnostic procedures, which require complete dilation of the pupil. |
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Authors:
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Cristina Artigas; José I Redondo; María M López-Murcia |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-31 |
Journal Detail:
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Title: Veterinary ophthalmology Volume: - ISSN: 1463-5224 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-11-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100887377 Medline TA: Vet Ophthalmol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 American College of Veterinary Ophthalmologists. |
Affiliation:
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Animal Medicine and Surgery Department, Cardenal Herrera-CEU University, Ed. Seminario s/n, 46113 Moncada, Valencia, Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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