Document Detail


Effects of intravenous administration of dexmedetomidine on intraocular pressure and pupil size in clinically normal dogs.
MedLine Citation:
PMID:  22050915     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Objective  To evaluate the effects of the intravenous administration of dexmedetomidine on the intraocular pressure (IOP) and pupil size (PS) in normal dogs. Animals studied  Forty-two animals with no ocular abnormalities were included in this study. Procedure  Following initial readings (T(0) ) of IOP and PS, the dogs received an intravenous injection of dexmedetomidine (5 μg/kg). Both measurements were repeated 10 min (T(10) ) and 20 min (T(20) ) later. Results  There were no significant differences in IOP measurements between T(0) and T(10) , although a significant decrease was observed at T(20) . A significant miosis was found in the first 10 min after sedation. At T(20) , the PS slightly increased, resulting in no statistical differences with T(0) and T(10) . Conclusion  Dexmedetomidine is an excellent option for surgery or diagnostic ocular procedures in dogs when a specific control of IOP is required. However, it must be used in combination with mydriatics in ophthalmic surgical or diagnostic procedures, which require complete dilation of the pupil.
Authors:
Cristina Artigas; José I Redondo; María M López-Murcia
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-10-31
Journal Detail:
Title:  Veterinary ophthalmology     Volume:  -     ISSN:  1463-5224     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-11-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100887377     Medline TA:  Vet Ophthalmol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 American College of Veterinary Ophthalmologists.
Affiliation:
Animal Medicine and Surgery Department, Cardenal Herrera-CEU University, Ed. Seminario s/n, 46113 Moncada, Valencia, Spain.
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