| Effects of intra-aortic balloon counterpulsation on coronary pressure in patients with stenotic coronary arteries. | |
| | |
MedLine Citation:
|
PMID: 17893000 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The benefits of intra-aortic balloon pumping (IABP) usage reportedly occur through systolic unloading of the left ventricle and the augmentation of diastolic coronary flow. The aim of this study was to assess the change in intracoronary pressure distal to the coronary stenosis after the IABP by using an intracoronary pressure wire. METHODS: Hemodynamic variables and intracoronary pressure data were measured in 16 patients requiring IABP for clinical indication (11 vessels with coronary stenosis and 5 normal vessels were enrolled). Coronary pressure was measured directly in each vessel with and without IABP support. RESULTS: The diastolic aortic pressure during IABP increased compared with that without the IABP (97.9 +/- 11.7 vs 80.3 +/- 10.7 mm Hg, P < .01). The systolic aortic and intracoronary pressure during the IABP decreased (aortic pressure: 83.8 +/- 10.4 vs 95.9 +/- 11.3 mm Hg, P < .01, intracoronary pressure: 67.6 +/- 16.5 vs 76.2 +/- 20.4 mm Hg, P < .01). The diastolic distal coronary pressure (Pd) increased during the IABP in healthy coronary arteries (87.3 +/- 4.8 vs 72.1 +/- 10.3 mm Hg, P < .05). However, Pd in stenotic coronary arteries with the IABP did not increase statistically compared with those without the IABP (44.0 +/- 21.3 vs 42.8 +/- 17.9 mm Hg). There was a significant correlation between the change in Pd after IABP insertion and percent diameter stenosis calculated by quantitative coronary angiography (r2 = 0.51, P < .001). CONCLUSIONS: In the presence of a critical coronary stenosis, the IABP does not increase the diastolic coronary pressure distal to the stenosis. Thus, the major effect of IABP on high-risk patients with severe coronary stenosis may relate to the reduction of oxygen demand by systolic unloading more than diastolic augmentation of the coronary flow. |
| | |
Authors:
|
Hidetoshi Yoshitani; Takashi Akasaka; Shuichiro Kaji; Takahiro Kawamoto; Teruyoshi Kume; Yoji Neishi; Yuji Koyama; Kiyoshi Yoshida |
Publication Detail:
|
Type: Journal Article; Randomized Controlled Trial |
Journal Detail:
|
Title: American heart journal Volume: 154 ISSN: 1097-6744 ISO Abbreviation: Am. Heart J. Publication Date: 2007 Oct |
Date Detail:
|
Created Date: 2007-09-25 Completed Date: 2007-11-06 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: United States |
Other Details:
|
Languages: eng Pagination: 725-31 Citation Subset: AIM; IM |
Affiliation:
|
Department of Internal Medicine and Cardiology, Graduate School of Medicine, Osaka City University, Osaka, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Angioplasty, Transluminal, Percutaneous Coronary Blood Pressure* Coronary Angiography Coronary Disease / therapy Coronary Stenosis / physiopathology* Coronary Vessels / physiopathology* Diastole / physiology Female Humans Intra-Aortic Balloon Pumping* Male Middle Aged Oxygen Consumption / physiology Systole / physiology |
| Comments/Corrections | |
Comment In:
|
Am Heart J. 2007 Oct;154(4):615-6
[PMID:
17892980
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A 6-month randomized pilot study of black tea and cardiovascular risk factors.
Next Document: Dual antiplatelet agent failure: a new syndrome or clinical nonentity?