Document Detail


Effects of interference stimuli on the acquisition of learned aversions to foods in the rat.
MedLine Citation:
PMID:  7430474     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A learned food aversion paradigm was developed to investigate characteristics of aversion learning likely to be involved in nutrient selection. The development of aversions to a relatively familiar, complete food was examined in rats with continuous access to that food. Learned food aversions were observed which were specific to the particular diet present during a sequence of toxic drug injections. In subsequent studies, novel liquids and solids were introduced in association with drug treatment to examine their effectiveness as interference stimuli. Flavored solutions, which have previously been reported to interfere with conditioned taste aversions, had little or no effect on learned aversions to the diet. This lack of interference by novel flavored liquids was coupled with significant conditioned aversions to the novel liquids themselves. Novel flavored solutions were contrasted with novel foods, which were extremely effective as interference stimuli in this paradigm. Possible bases for the observed differences in interference effects of foods and drinks are examined.
Authors:
I L Bernstein; M V Vitiello; R A Sigmundi
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of comparative and physiological psychology     Volume:  94     ISSN:  0021-9940     ISO Abbreviation:  J Comp Physiol Psychol     Publication Date:  1980 Oct 
Date Detail:
Created Date:  1981-01-16     Completed Date:  1981-01-16     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0414612     Medline TA:  J Comp Physiol Psychol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  921-31     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Association Learning / drug effects
Avoidance Learning* / drug effects
Cyclophosphamide / poisoning
Drinking / drug effects
Eating* / drug effects
Male
Rats
Taste / drug effects
Grant Support
ID/Acronym/Agency:
CA26419/CA/NCI NIH HHS
Chemical
Reg. No./Substance:
50-18-0/Cyclophosphamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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