Document Detail

Effects of insulin on glycogen metabolism in isolated and perfused catfish liver.
MedLine Citation:
PMID:  2858286     Owner:  NLM     Status:  MEDLINE    
The isolated and perfused catfish liver showed (a) a decrease in liver glycogen, (b) a continuous increase in glucose output, and (c) a decrease of lactate in the medium. Insulin did not influence liver glycogen decay during the first 2 hr; thereafter the hormone induced an increase of glycogen, particularly when glucose was added into perfusate. In insulin treated liver, the glucose output was lower than controls in the first hours of perfusion; thereafter a re-uptake of glucose occurred. After 2-3 hr of perfusion, the lactate present in the medium was increased by insulin towards the starting level. The long lasting effects of insulin on catfish in vivo were confirmed.
C Ottolenghi; A C Puviani; M E Gavioli; L Brighenti
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Publication Detail:
Type:  Comparative Study; In Vitro; Journal Article    
Journal Detail:
Title:  Comparative biochemistry and physiology. A, Comparative physiology     Volume:  80     ISSN:  0300-9629     ISO Abbreviation:  Comp Biochem Physiol A Comp Physiol     Publication Date:  1985  
Date Detail:
Created Date:  1985-04-26     Completed Date:  1985-04-26     Revised Date:  2008-10-30    
Medline Journal Info:
Nlm Unique ID:  1276312     Medline TA:  Comp Biochem Physiol A Comp Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  135-8     Citation Subset:  IM    
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MeSH Terms
Fishes / metabolism*
Glucose / metabolism
Insulin / pharmacology*
Lactates / metabolism
Lactic Acid
Liver / drug effects*,  metabolism
Liver Glycogen / metabolism*
Reg. No./Substance:
0/Lactates; 0/Liver Glycogen; 11061-68-0/Insulin; 50-21-5/Lactic Acid; 50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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