Document Detail


Effects of injury to the right ventricular conducting tissue of canine hearts on epicardial activation sequence and electrocardiograms.
MedLine Citation:
PMID:  7300018     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The distal right ventricular conducting tissues of 45 canine hearts were experimentally interrupted in various degrees by a transmural incision of the right ventricular free wall, a trans-section of the lateral branches of the right bundle or by injury to the endocardial Purkinje network. Right ventriculotomy caused a slight activation delay (less than 10 msec) of the right ventricle which was restricted to the distal area from the incision, but the delay was not long enough to cause a significant prolongation of the QRS duration in the limb lead ECG. In one experiment, a vertical incision in the middle region induced an exceptional, marked alteration of the right ventricular activation sequence and an apparent prolongation of the QRS duration (16 msec) indicating an incomplete RBBB. However, anatomical analysis revealed that the lateral branches were nearly completely interrupted by the incision. An extensive injury to the Purkinje network extending toward the right ventricular outflow tract by a blunt scalpel caused a local activation delay in the outflow tract, without producing any serious delay resulting in an ECG pattern of RBBB. These results may suggest that right ventriculotomy would induce the RBBB pattern of ECG if lateral branches are extensively injured by the surgical procedure, and that the injury to the Purkinje network extending toward the outflow tract does not play a primary role of genesis of RBBB pattern in ECG.
Authors:
M Ohno; J Toyama; T Kohbe; S Isomura; I Kodama; K Yamada
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Japanese circulation journal     Volume:  45     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1981 Sep 
Date Detail:
Created Date:  1982-01-20     Completed Date:  1982-01-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  1056-67     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Action Potentials*
Animals
Atrioventricular Node / surgery
Bundle-Branch Block / surgery
Dogs
Electrocardiography*
Heart Conduction System / injuries*
Heart Ventricles / injuries*
Purkinje Fibers / injuries

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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