Document Detail


Effects of increasing the rate of alcohol metabolism on plasma acetate concentration.
MedLine Citation:
PMID:  1580924     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Plasma acetate concentration is increased during alcohol metabolism. However, measures which increase the rate of alcohol metabolism do not always increase plasma acetate concentration. Plasma samples from normal male subjects who had been given alcohol and then either fructose or glucose were analysed for acetate. Although each of these carbohydrates increased the mean rate of alcohol metabolism, only fructose increased the plasma acetate concentration. It was concluded that the further metabolism of acetate produced from alcohol may be increased by glucose.
Authors:
D Mascord; J Smith; G A Starmer; J B Whitfield
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Alcohol and alcoholism (Oxford, Oxfordshire)     Volume:  27     ISSN:  0735-0414     ISO Abbreviation:  Alcohol Alcohol.     Publication Date:  1992 Jan 
Date Detail:
Created Date:  1992-06-18     Completed Date:  1992-06-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8310684     Medline TA:  Alcohol Alcohol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  25-8     Citation Subset:  IM    
Affiliation:
Department of Pharmacology, University of Sydney, NSW, Australia.
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MeSH Terms
Descriptor/Qualifier:
Acetates / blood*
Administration, Oral
Alcoholism / blood*
Ethanol / pharmacokinetics*
Fructose / administration & dosage
Glucose Solution, Hypertonic / administration & dosage
Humans
Infusions, Intravenous
Male
Metabolic Clearance Rate / physiology
Chemical
Reg. No./Substance:
0/Acetates; 0/Glucose Solution, Hypertonic; 30237-26-4/Fructose; 64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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