Document Detail


Effects of increased +Gz on chest wall mechanics in humans.
MedLine Citation:
PMID:  7775346     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We studied the effects of head-to-foot acceleration (+Gz) on chest wall mechanics in five normal subjects seated in a human centrifuge. Results were compared with those previously obtained in the same subjects in microgravity during parabolic flights. In all subjects, end-expiratory abdominal pressure (Pga) and volume (Vab) increased with Gz. On average, end-expiratory Pga increased from 7.4 +/- 1.7 cmH2O at + 1 Gz to 14.9 +/- 2.8 cmH2O at + 3 Gz and end-expiratory Vab increased by 0.32 +/- 0.06 liter between + 1 and + 3 Gz. On the other hand, the abdominal contribution to tidal volume (Vab/VT) and abdominal compliance decreased from 34.7 +/- 5.9% and 52 +/- 6 ml/cmH2O at + 1 Gz to 29.3 +/- 5.1% and 26 +/- 4 ml/cmH2O at + 3 Gz, respectively. Changes in end-expiratory Pga were linear between 0 and + 3 Gz, but changes in end-expiratory Vab, Vab/VT, and abdominal compliance were greater in microgravity than in hypergravity. In contrast to weightlessness, which did not alter minute ventilation and tidal changes in Pga and transdiaphragmatic pressure, these variables increased with increasing Gz. These results indicate that, although changes in Gz have a linear effect on abdominal transmural pressure, hypergravity and weightlessness do not have symmetrical effects on chest wall mechanics.
Authors:
M Estenne; A Van Muylem; W Kinnear; M Gorini; V Ninane; L A Engel; M Paiva
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  78     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  1995 Mar 
Date Detail:
Created Date:  1995-07-11     Completed Date:  1995-07-11     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  997-1003     Citation Subset:  IM; S    
Affiliation:
Chest Service, Erasme University Hospital, Brussels, Belgium.
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MeSH Terms
Descriptor/Qualifier:
Abdomen / physiology
Abdominal Muscles / physiology
Adult
Compliance
Electromyography
Gravitation*
Humans
Male
Middle Aged
Pressure
Respiration
Respiratory Physiological Phenomena
Stomach / physiology
Thorax / physiology*
Tidal Volume

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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