| Effects of hypothermia on mortality and inflammatory responses to endotoxin-induced shock in rats. | |
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MedLine Citation:
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PMID: 12965930 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We studied the effects of hypothermia on mortality rate, concentrations of tumor necrosis factor alpha and interleukin 6 in plasma, and the end products of nitric oxide (NO) in endotoxemia. It was found that moderate and mild hypothermia improved the mortality rate and attenuated cytokine responses and the elevation of the end products of NO after endotoxin injection and that these beneficial effects were similar for moderate and mild hypothermia. |
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Authors:
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Takumi Taniguchi; Hiroko Kanakura; Yasuhiro Takemoto; Ken Yamamoto |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Clinical and diagnostic laboratory immunology Volume: 10 ISSN: 1071-412X ISO Abbreviation: Clin. Diagn. Lab. Immunol. Publication Date: 2003 Sep |
Date Detail:
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Created Date: 2003-09-10 Completed Date: 2004-05-20 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 9421292 Medline TA: Clin Diagn Lab Immunol Country: United States |
Other Details:
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Languages: eng Pagination: 940-3 Citation Subset: IM |
Affiliation:
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Department of Emergency and Critical Care Medicine, Graduate School of Medical Science, Kanazawa University Graduate School of Medical Science, Kanazawa University, Kanazawa 920-8641, Japan. taniyan@med.kanazawa-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Endotoxins / adverse effects* Hypothermia, Induced* Inflammation / metabolism*, therapy Interleukin-6 / blood Male Nitric Oxide / blood, metabolism Rats Rats, Wistar Shock, Septic / therapy* Tumor Necrosis Factor-alpha / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Endotoxins; 0/Interleukin-6; 0/Tumor Necrosis Factor-alpha; 10102-43-9/Nitric Oxide; 67924-63-4/endotoxin, Escherichia coli |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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