| Effects of hyperthermia on plasma glycoprotein catabolism by the isolated perfused rat liver. | |
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MedLine Citation:
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PMID: 6136373 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Clearance and degradation of the glycoprotein, asialofetuin (AF), by the isolated perfused rat liver at supranormal temperatures were investigated. The half-life for disappearance of AF was similar at 37, 41, and 42 degrees C, P greater than 0.05. There was a significant difference between the amount of hydrolysis of AF at 37, 41, and 42 degrees C, P less than 0.05. This indicates that there was significant retardation of lysosomal proteolysis or receptor endocytosis by the hepatocyte at elevated temperatures. |
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Authors:
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J L Skibba; L P McKean; J L Winkelhake |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Comparative biochemistry and physiology. A, Comparative physiology Volume: 75 ISSN: 0300-9629 ISO Abbreviation: Comp Biochem Physiol A Comp Physiol Publication Date: 1983 |
Date Detail:
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Created Date: 1983-10-08 Completed Date: 1983-10-08 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 1276312 Medline TA: Comp Biochem Physiol A Comp Physiol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 391-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Glycoproteins / blood, metabolism* Hot Temperature* Iodine Radioisotopes / diagnostic use Liver / metabolism* Male Rats Rats, Inbred Strains Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Glycoproteins; 0/Iodine Radioisotopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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