Document Detail

Effects of hypercapnia and arterial hypotension and hypertension on cerebrospinal fluid pulse pressure and intracranial volume-pressure relationships.
MedLine Citation:
PMID:  7373319     Owner:  NLM     Status:  MEDLINE    
In twelve anaesthetised, ventilated dogs the effects of hypercapnia and pharmacologically induced arterial hypotension and hypertension on the interrelation between volume-pressure response (VPR) and cerebro-spinal fluid (CSF) pulse pressure were studied during continuous inflation of a supratentorial extradural balloon. Hypercapnia did not significantly affect the intracranial volume-pressure relationships, but did cause a significant increase in gradient of the relationship between CSF pulse pressure and intracranial pressure (ICP). Alteration of the arterial blood pressure showed opposite effects on VPR and CSF pulse pressure. A decrease in VPR and an increase in pulse pressure were observed during arterial hypotension; the reverse was found during arterial hypertension. The discrepancy between the effects on VPR and CSF pulse pressure of the variables under study was explained by changes in the transient increase in cerebral blood volume per cardiac cycle. On the basis of the results of this study it will be possible, during clinical ICP monitoring, to interpret changes in the CSF pulse pressure to ICP ratio in terms of changes in intracranial volume-pressure relationships.
C J Avezaat; J H van Eijndhoven; D J Wyper
Related Documents :
4045519 - A new method for noninvasive measurement of short-term cerebrospinal fluid pressure cha...
3128529 - Dids decreases csf hco3- and increases breathing in response to co2 in awake rabbits.
22129089 - Remote monitoring of lower-limb prosthetic socket fit using wireless technologies.
20831359 - Comparison between 3 infusion methods to measure cerebrospinal fluid outflow conductance.
1029639 - Effect of moderate arterial hypotension combined with repeated withdrawal of cerebrospi...
14587649 - Shifting of puncture site in the fossa ovalis during radiofrequency catheter ablation: ...
19131449 - Risk factors for complicated parapneumonic effusion and empyema on presentation to hosp...
16077269 - Validation of semi-automatic device ua-704 for self-measurement of blood pressure.
6876379 - Cardiovascular response to a mentally stressful stimulus.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  43     ISSN:  0022-3050     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  1980 Mar 
Date Detail:
Created Date:  1980-07-12     Completed Date:  1980-07-12     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  222-34     Citation Subset:  IM; S    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Blood Pressure
Blood Volume
Brain / blood supply
Heart Rate
Hypercapnia / cerebrospinal fluid*
Hypertension / cerebrospinal fluid*
Hypotension / cerebrospinal fluid*
Intracranial Pressure

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A clinical comparative study of multiple sclerosis and neuro-Behçet's syndrome.
Next Document:  The relationship between tactile thresholds and histology in the human finger.