| Effects of hydroxyurea on the phagocytosis of microspheres in V79 cells. | |
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MedLine Citation:
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PMID: 2553279 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Phagocytosis of fluorescent microspheres in V79 cells arrested in the S phase by hydroxyurea (HU) was investigated by flow cytometry. The phagocytic activity increased with the exposure time of HU. No dependency on the HU concentration was observed in the concentration used. Cell size (projection area) and membrane fluidity, two factors effected by HU treatment, were examined in relation to phagocytic activity, and were found to be significantly increased. The elevation in phagocytic activity could be interpreted in terms of the alteration in the two physiological factors. |
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Authors:
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K Fujikawa-Yamamoto; S Odashima |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Cell structure and function Volume: 14 ISSN: 0386-7196 ISO Abbreviation: Cell Struct. Funct. Publication Date: 1989 Aug |
Date Detail:
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Created Date: 1989-11-29 Completed Date: 1989-11-29 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7608465 Medline TA: Cell Struct Funct Country: JAPAN |
Other Details:
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Languages: eng Pagination: 485-93 Citation Subset: IM |
Affiliation:
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Department of Pathology, Kanazawa Medical University, Ishikawa, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Line Cell Membrane / physiology, ultrastructure Cricetinae Cricetulus Electron Spin Resonance Spectroscopy Flow Cytometry Hydroxyurea / pharmacology* Lung / cytology*, ultrastructure Membrane Fluidity / drug effects Microspheres Phagocytosis / drug effects* |
| Chemical | |
Reg. No./Substance:
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127-07-1/Hydroxyurea |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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