Document Detail

Effects of human milk fortifier on the antimicrobial properties of human milk.
MedLine Citation:
PMID:  17024140     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the effects of addition of human milk (HM) fortifier and iron on the anti-infective properties of HM. STUDY DESIGN: HM samples were collected from 28 lactating mothers who delivered prematurely, within the first week of post-natal life. HM fortifier Eoprotin was used. The effects of this fortifier against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans were evaluated using a filter paper method. The measurements were repeated with pure HM, fortified HM and iron-added HM. RESULTS: HM inhibited the growth of S. aureus, E. coli, P. aeruginosa and Candida. Addition of HM fortifier did not result in any significant difference on this effect. The addition of iron to HM reduced antimicrobial effect against all three bacteria and the Candida. CONCLUSION: Premature HM has strong antimicrobial activity and addition of the milk fortifier Eoprotin does not change this effect, but addition of iron reduces this antimicrobial activity.
F Ovali; Ih Ciftçi; Z Cetinkaya; A Bükülmez
Publication Detail:
Type:  Journal Article     Date:  2006-10-05
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  26     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-23     Completed Date:  2007-03-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  761-3     Citation Subset:  IM    
Department of Pediatrics, Neonatal Intensive Care Unit, Afyon Kocatepe University, Afyonkarahisar, Turkey.
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MeSH Terms
Candida albicans / growth & development*
Escherichia coli / growth & development*
Food, Fortified*
Iron / administration & dosage
Milk, Human / immunology*
Pseudomonas aeruginosa / growth & development*
Staphylococcus aureus / growth & development*
Reg. No./Substance:

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