Document Detail


Effects of high and low glycemic load meals on energy intake, satiety and hunger in obese Hispanic-American youth.
MedLine Citation:
PMID:  21309658     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To examine the effects of LGL and high-GL (HGL) meals on appetitive responses and ad libitum energy intake of obese Hispanic youth.
METHODS: A total of 88 obese Hispanic youth aged 7-15 years were enrolled in a community-based obesity intervention program and randomly assigned to consume meals designed as either LGL (n = 45) or HGL (n = 43). After 12 weeks, participants were admitted for a 24-hour metabolic study. Following the morning test meal, subjects serially reported hunger, fullness, and satiety using a visual analog scale. Blood insulin and glucose were measured. After 5 hours, participants were fed another test meal and given a snack platter from which to eat ad libitum. All test food was weighed and the energy, macronutrients, and glycemic load (GL) of consumed foods were calculated.
RESULTS: The HGL group had significantly higher insulin (p = 0.0005) and glucose (p = 0.0001) responses to the breakfast meal compared with the LGL group. There were no significant between-group differences in energy consumed from the snack platter (1303 vs. 1368 kcal, p = 0.5), or in the subjective feelings of hunger (p = 0.3), fullness (p = 0.5) or satiety (p = 0.3) between the two groups.
CONCLUSIONS: Our study provides no evidence that, for obese Hispanic youth, changing the GL of the diet affects short-term hunger, fullness, satiety, or energy intake. ClinicalTrials.gov Identifier: NCT01068197.
Authors:
Nazrat M Mirza; Catherine J Klein; Matilde G Palmer; Robert McCarter; Jianping He; Cara B Ebbeling; David S Ludwig; Jack A Yanovski
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't     Date:  2011-02-10
Journal Detail:
Title:  International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity     Volume:  6     ISSN:  1747-7174     ISO Abbreviation:  Int J Pediatr Obes     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-07-01     Completed Date:  2011-10-28     Revised Date:  2012-03-07    
Medline Journal Info:
Nlm Unique ID:  101256330     Medline TA:  Int J Pediatr Obes     Country:  England    
Other Details:
Languages:  eng     Pagination:  e523-31     Citation Subset:  IM    
Affiliation:
Children's National Medical Center, Washington, DC, USA. nmirza@cnmc.org
Data Bank Information
Bank Name/Acc. No.:
ClinicalTrials.gov/NCT01068197
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adolescent Behavior / ethnology*
Age Factors
Blood Glucose / metabolism
Child
Child Behavior / ethnology*
District of Columbia / epidemiology
Energy Intake / ethnology*
Feeding Behavior / ethnology*
Female
Glycemic Index*
Hispanic Americans / psychology*
Humans
Hunger / ethnology*
Insulin / blood
Male
Obesity / blood,  diet therapy*,  ethnology,  psychology
Satiety Response*
Time Factors
Treatment Outcome
Grant Support
ID/Acronym/Agency:
K23 RR022227-03/RR/NCRR NIH HHS; K23-RR022227/RR/NCRR NIH HHS; K24 DK082730-03/DK/NIDDK NIH HHS; K24DK082730/DK/NIDDK NIH HHS; MO1-RR-020359/RR/NCRR NIH HHS; R01 DK070260-15/DK/NIDDK NIH HHS; Z99 HD999999/HD/NICHD NIH HHS; ZIA HD000641-15/HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Insulin
Comments/Corrections

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