Document Detail


Effects of high-frequency chest wall oscillation on pleural pressure and oscillated flow.
MedLine Citation:
PMID:  19012467     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effectiveness of high-frequency chest wall oscillation (HF-CWO) is directly related to the level of oscillated flow (osc) in the airways. We used the Vest system to investigate the effects of HFCWO on chest wall and pleural pressures and we correlated these pressures to the resultant osc. We also compared the latest HFCWO device with it predecessor. Different combinations of vest inflation pressure (background pressure) and oscillation frequency were randomly applied to 10 healthy volunteers. Chest wall pressure was determined using an air-filled bag under the vest and pleural pressure was estimated using an esophageal balloon. Reverse plethysmography was used to measure osc at the mouth and a spirometer was used to measure changes in end-expired lung volume. We found a significant correlation between chest wall and pleural pressure with approximately one-third of the chest wall pressure transmitted into the pleural space. Mean esophageal pressure remained negative at all background pressure/frequency combinations. There was a significant correlation (p<0.0001) between the esophageal pulse pressure and osc, which was highest at 15Hz regardless of the background pressure. The end-expired lung volume correlated with mean chest wall pressure. There was no significant difference between the two Vest systems. Since osc dictates the effectiveness of HFCWO and since osc is dependent on esophageal pulse pressure, which in turn is dependent on chest wall pulse pressure, it follows that the effectiveness of HFCWO is influenced by the ability to generate an effective chest wall pulse pressure.
Authors:
Tal Zucker; Neil M Skjodt; Richard L Jones
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biomedical instrumentation & technology / Association for the Advancement of Medical Instrumentation     Volume:  42     ISSN:  0899-8205     ISO Abbreviation:  Biomed Instrum Technol     Publication Date:    2008 Nov-Dec
Date Detail:
Created Date:  2008-11-17     Completed Date:  2009-02-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8905560     Medline TA:  Biomed Instrum Technol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  485-91     Citation Subset:  IM    
Affiliation:
Department of Medicine, Pulmonary Division, University of Alberta, Edmonton, Alberta, Canada.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Blood Pressure / physiology*
Chest Wall Oscillation / instrumentation*,  methods*
Esophagus / physiology*
Female
Humans
Male
Middle Aged
Respiratory Mechanics / physiology*
Thorax / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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