Document Detail

Effects of gravitational stresses on mitral valve prolapse. I. Changes in auscultatory findings produced by progressive passive head-up tilt.
MedLine Citation:
PMID:  656212     Owner:  NLM     Status:  MEDLINE    
The effects of passive head-up tilt on systolic time intervals were assessed in 18 patients with mitral valve prolapse. In addition to causing prolongation of the pre-ejection period and shortening of left ventricular ejection time, this circulatory stress led to progressive shortening of the Q to click interval. In 1 patient, a systolic click became audible which had not been heard in the supine posture. In 7 patients the click disappeared during head-up tilt, usually at 60 degrees or 90 degrees. In 2 patients without a murmur while supine, a mid-late systolic murmur appeared with tilt; 1 of these 2 as well as another patient who had a soft late systolic murmur while supine developed loud systolic whoops at greater angles of tile. The correlations between Q to click interval and aortic valve opening to click interval, and both the angle and the sine of the angle of tilt were highly significant.
W D Towne; R Patel; J Cruz; N Kramer; K K Chawla
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British heart journal     Volume:  40     ISSN:  0007-0769     ISO Abbreviation:  Br Heart J     Publication Date:  1978 May 
Date Detail:
Created Date:  1978-08-28     Completed Date:  1978-08-28     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370634     Medline TA:  Br Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  482-8     Citation Subset:  AIM; IM; S    
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MeSH Terms
Heart Rate
Heart Sounds
Middle Aged
Mitral Valve Insufficiency / physiopathology*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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