Document Detail


Effects of genetic selection on growth rate and intestinal structure in the domestic fowl (Gallus domesticus).
MedLine Citation:
PMID:  1979266     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. Pieces of small intestine taken from chickens subjected previously to continuous selection, relaxed selection or no selection for rapid growth were used to estimate villus surface area and microvillus development to determine what effects genetic selection might have on factors controlling intestinal function. 2. Crypt size and the rates at which enterocytes migrated out of crypts were also measured, after injection of tritiated thymidine, to determine the time course of microvillus elongation. 3. Differences in growth rates measured between highly selected, relaxed selected or unselected birds were found to be correlated with parallel changes in villus surface area. Selection for growth did not change the density, dimensions or pattern of development of enterocyte microvilli. Microvilli did, however, produce a maximal 20-fold increase in villus surface area under all conditions. 4. Crypt size and enterocyte migration rates did not vary significantly between tissue taken from unselected and relaxed selected chickens. Tissue taken from highly selected birds had a crypt size and enterocyte migration rate 40% higher than values found for the other two groups of chickens. 5. The possibility that early genetic selection increased growth potential by uncoupling diet-induced changes on crypt hyperplasia from secondary effects on villus structure, and that later selection increased growth potential by increasing appetite, is discussed.
Authors:
M W Smith; M A Mitchell; M A Peacock
Related Documents :
7171496 - Intraventricular conduction time in fetuses born with growth retardation.
16790736 - The late effects of fetal growth patterns.
3149956 - Longitudinal studies of femur growth in normal fetuses.
22281076 - Inclusion of bovine lipoproteins and the vitamin e analogue, trolox, during in vitro cu...
16727316 - Use of pregnancy-specific protein-b and estrone sulfate for determination of pregnancy ...
7066256 - Factors associated with preterm labour and changes in the cervix before labour in twin ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Comparative biochemistry and physiology. A, Comparative physiology     Volume:  97     ISSN:  0300-9629     ISO Abbreviation:  Comp Biochem Physiol A Comp Physiol     Publication Date:  1990  
Date Detail:
Created Date:  1991-01-22     Completed Date:  1991-01-22     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  1276312     Medline TA:  Comp Biochem Physiol A Comp Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  57-63     Citation Subset:  IM    
Affiliation:
AFRC Institute of Animal Physiology and Genetics Research, Babraham, Cambridge, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cell Movement
Chickens / anatomy & histology,  genetics*,  growth & development
Female
Intestine, Small / anatomy & histology*,  growth & development,  physiology
Microvilli / ultrastructure
Selection, Genetic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Temperature regulation and basal metabolic rate in the spotted skunk, Spilogale putorius.
Next Document:  Role of Ca2+ and prostaglandin in regulation of active Na+ transport in frog skin.