Document Detail

Effects of gastroesophageal reflux on esophageal motility.
MedLine Citation:
PMID:  23330291     Owner:  NLM     Status:  In-Process    
METHODS: A stationary esophageal manometry and a questionnaire of gastrointestinal symptoms were performed on 41 individuals, of whom 13 (31.7%) complained of gastroesophageal reflux.
RESULTS: The following data were obtained in cases of non-reflux vs. reflux: mean wave amplitude, 53.4 +/- 17.9 mm Hg vs. 48.6 +/- 11.8 mm Hg; similar mean upstroke; and lower esophageal sphincter pressure of 16.7 +/- 6.4 mm Hg vs. 17.9 +/- 4.9 mm Hg (p = 0.5). The relaxing degree and duration were similar. In the analysis according to the severity of the symptoms, we verified the following differences between cases of slight and severe reflux: amplitude in proximal esophagus, 40.75 +/- 13.1 mm Hg sec vs. 23.0 +/- 9.2 mm Hg sec (p = 0.02); mean average upstroke, 36.6 +/- 8.2 mm Hg sec vs. 24.8 +/- 7.3 mm Hg sec (p = 0.02); mean maximum upstroke, 61.4 +/- 10.4 mm Hg sec vs. 47.0 +/- 12.4mm Hg sec (p = 0.04); and relaxing duration, 5.36 +/- 2.0 sec vs. 8.76 +/- 1.6 sec (p = 0.01).
CONCLUSIONS: 1. No differences in the manometric characteristics of the esophagus were found between individuals with and without reflux. 2. The wave amplitude and the upstroke were significantly higher in the proximal esophagus of patients with less severe complaints. 3. The mean and maximum upstroke of the esophageal wave were lower in individuals with severe reflux. 4. The relaxation duration was higher in patients with severe complaints.
J X Jorge; C C Almeida; Cláudia Iracema Cardoso Borges; F J Delgado; M A Simões; A L Silva; A C Coelho
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Romanian journal of internal medicine = Revue roumaine de médecine interne     Volume:  50     ISSN:  1220-4749     ISO Abbreviation:  Rom J Intern Med     Publication Date:    2012 Jul-Sep
Date Detail:
Created Date:  2013-01-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9304507     Medline TA:  Rom J Intern Med     Country:  Romania    
Other Details:
Languages:  eng     Pagination:  233-9     Citation Subset:  IM    
Faculty of Medicine, University of Coimbra.
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