Document Detail


Effects of galactose, mannitol, glucose and alpha-methyl-D-glucoside on the incorporation of 32P-inorganic phosphate into phospholipids in Hymenolepis diminuta (Cestoda).
MedLine Citation:
PMID:  2513354     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the presence of glucose and galactose, the incorporation of radioactive inorganic phosphate (32Pi) into phosphatidylcholine of Hymenolepis diminuta was significantly lowered as compared to the control, whereas other phospholipids remained unaffected. alpha-methyl-D-glucoside, however, significantly lowered the amount of 32Pi incorporated into phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and phosphatidic acid. Mannitol did not have any effect on the incorporation of 32Pi into the phospholipids of H. diminuta. The effect of glucose and alpha-methylglucoside on phospholipid metabolism was both time and concentration dependent. The inorganic, organic, total and phosphatidylcholine-bound phosphate of H. diminuta in the presence of various substrates were not significantly different from the control values under all incubation conditions. The results indicate that the observations made in the presence of external glucose, galactose and alpha-methylglucoside were due to their physical interaction with the transport mechanism in the tegumental membrane of H. diminuta and also their being subsequently metabolized in the cases of the former two hexoses.
Authors:
Y K Ip; M M Khan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of helminthology     Volume:  63     ISSN:  0022-149X     ISO Abbreviation:  J. Helminthol.     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-02-06     Completed Date:  1990-02-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985115R     Medline TA:  J Helminthol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  338-48     Citation Subset:  IM    
Affiliation:
Department of Zoology, National University of Singapore, Kent Ridge.
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MeSH Terms
Descriptor/Qualifier:
Animals
Galactose / metabolism
Glucose / metabolism
Hymenolepis / metabolism*
Isotope Labeling
Mannitol / metabolism
Methylglucosides / metabolism
Phosphates / metabolism*
Phospholipids / metabolism*
Phosphorus Radioisotopes
Chemical
Reg. No./Substance:
0/Methylglucosides; 0/Phosphates; 0/Phospholipids; 0/Phosphorus Radioisotopes; 25360-07-0/methylglucoside; 26566-61-0/Galactose; 50-99-7/Glucose; 69-65-8/Mannitol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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