Document Detail


Effects of furosemide on the racing times of horses with exercise-induced pulmonary hemorrhage.
MedLine Citation:
PMID:  4014825     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In 3 groups of horses with exercise-induced pulmonary hemorrhage (EIPH), comparisons of racing times and finishing positions were made between the 5 races before the horses were given furosemide and 5 races after furosemide administration. The horses were grouped according to 3 methods used to diagnose EIPH: group 1, observation of hemorrhage at the nostrils within 1 hour after a workout or race; group 2, observation of pulmonary hemorrhage only by endoscopic examination after a race or workout; and group 3, observation of hemorrhage at the nostrils during a race or immediately after a race. Group 4 horses were randomly selected horses running during the study period and were not given furosemide. The statistical method was analysis of covariance and the dependent variable was horses' time per distance. The study compared the 4 groups of horses, using the estimated value of the horses (less than or equal to +10,000 or greater than +10,000), and the horses' interaction in races 1 through 5 before and races 6 through 10 after furosemide treatment. The horses' times were adjusted by the relevant covariates, distance, track variant, and winning time per distance. Significant changes in horses' time per distance were not noticed when comparing values from races 1 through 5 with those in races 6 through 10 in group 1 horses.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
L R Soma; L Laster; F Oppenlander; V Barr-Alderfer
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of veterinary research     Volume:  46     ISSN:  0002-9645     ISO Abbreviation:  Am. J. Vet. Res.     Publication Date:  1985 Apr 
Date Detail:
Created Date:  1985-08-05     Completed Date:  1985-08-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375011     Medline TA:  Am J Vet Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  763-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Furosemide / pharmacology*,  therapeutic use
Hemorrhage / drug therapy,  physiopathology,  veterinary*
Horse Diseases / drug therapy,  physiopathology*
Horses
Lung Diseases / drug therapy,  physiopathology,  veterinary*
Running*
Chemical
Reg. No./Substance:
54-31-9/Furosemide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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