Document Detail


Effects of furosemide, exercise, and atropine on tracheal mucus transport rate in horses.
MedLine Citation:
PMID:  7574159     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Effects of furosemide, exercise, and atropine on tracheal mucus transport rate (TMTR) in horses were investigated. Atropine (0.02 mg/kg of body weight) administered IV or by aerosolization significantly (P < 0.05) decreased TMTR at 60, but not at 30 minutes after its administration in standing horses. Furosemide (1.10 mg/kg, IV) did not have any significant effect on TMTR when measured at 2 or 4 hours after its administration in standing horses. Exercise alone or furosemide (1.10 mg/kg, IV) administration followed 4 hours later by exercise did not alter TMTR, compared with values for standing control or exercised horses administered saline solution. Atropine (0.02 mg/kg, IV) administered after exercise significantly (P < 0.05) decreased TMTR, compared with values for no exercise standing controls, for exercise after administration of saline solution, and for furosemide and exercise.
Authors:
A D Maxson; L R Soma; L L May; J A Martini
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of veterinary research     Volume:  56     ISSN:  0002-9645     ISO Abbreviation:  Am. J. Vet. Res.     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1995-11-09     Completed Date:  1995-11-09     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0375011     Medline TA:  Am J Vet Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  908-12     Citation Subset:  IM    
Affiliation:
New Bolton Center, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, 19348-1692, USA.
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MeSH Terms
Descriptor/Qualifier:
Aerosols
Animals
Atropine / administration & dosage,  pharmacology*
Exercise Test / veterinary
Female
Furosemide / administration & dosage,  pharmacology*
Horses / physiology*
Injections, Intravenous
Male
Mucous Membrane / drug effects,  physiology
Orchiectomy
Physical Exertion*
Trachea / physiology*
Chemical
Reg. No./Substance:
0/Aerosols; 51-55-8/Atropine; 54-31-9/Furosemide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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