Document Detail

Effects of formalin feeding or administering into the crops of white leghorn cockerels on hematological and biochemical parameters.
MedLine Citation:
PMID:  16977835     Owner:  NLM     Status:  MEDLINE    
Formalin administered (15 and 20 mL) into the crops of White Leghorn cockerels resulted in behavioral alterations, included depression, dullness, staggering, somnolence, anorexia, and decreased frequency of crowing. A significant decrease was observed in red blood cell counts, hemoglobin concentration, packed cell volume, and leukocyte counts in birds fed higher levels of formalin. Decreasing and increasing trends in concentrations of serum proteins and enzymes, respectively, were observed with increases in formalin doses. Significantly lower blood glucose and testosterone levels and significantly (P < 0.05) higher blood urea and creatinine concentrations were observed in birds fed higher formalin levels. No gross or microscopic lesions were observed in the birds fed different levels of formalin mixed in feed. These changes suggested that the formalin mixed in feed might have evaporated, and, hence, the amount ingested might have been too low to induce pathological changes. It was concluded from the present study that formalin mixed up to 5 mL/kg of feed, corresponding to 10 mL/bird of 3% formalin in drinking water by crop tube had no adverse effects on the health of White Leghorn cockerels.
A Khan; S M Hussain; M Z Khan
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Poultry science     Volume:  85     ISSN:  0032-5791     ISO Abbreviation:  Poult. Sci.     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-09-18     Completed Date:  2006-10-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401150     Medline TA:  Poult Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1513-9     Citation Subset:  IM    
Department of Veterinary Pathology, University of Agriculture, Faisalabad-38040, Pakistan.
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MeSH Terms
Administration, Oral
Animal Feed
Blood Chemical Analysis / veterinary
Chickens / blood*
Crop, Avian / drug effects*
Disinfectants / administration & dosage*,  adverse effects*,  toxicity
Dose-Response Relationship, Drug
Formaldehyde / administration & dosage*,  adverse effects*,  toxicity
Reg. No./Substance:
0/Disinfectants; 50-00-0/Formaldehyde

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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