| Effects of focused force angioplasty: pre-clinical experience and clinical confirmation. | |
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MedLine Citation:
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PMID: 15831973 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Balloon angioplasty results in a combination of plaque compression and fracture, creation of intimal flaps and localized medial dissection, as well as the stretching and remodeling of the arterial wall. The application of eccentric pressure to the vessel wall allows for the balloon force to be focused along a specified line resulting in a reduction in vessel resistance with an improved or equivalent result at a lower pressure. The FX miniRAIL is a novel balloon angioplasty catheter that has two external wires that are compressed by the inflating balloon into the vessel wall. It was tested in comparison to conventional balloon injury in a porcine coronary model. At equivalent balloon artery ratios no increase in the length of dissections occurred, but a characteristic longitudinal "cut" was noted in the presence of the FX miniRAIL. A similar finding was demonstrated in sample human cases when interrogated by IVUS and OCT. |
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Authors:
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David Meerkin; Seung H Lee; Fermin O Tio; Erberharde Grube; S Chiu Wong; Mun K Hong |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The Journal of invasive cardiology Volume: 17 ISSN: 1042-3931 ISO Abbreviation: J Invasive Cardiol Publication Date: 2005 Apr |
Date Detail:
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Created Date: 2005-04-15 Completed Date: 2005-06-14 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8917477 Medline TA: J Invasive Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 203-6 Citation Subset: IM |
Affiliation:
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Shaare Zedek Medical Center, Department of Cardiology, P.O.B. 3235, Jerusalem, Israel 91031. meerkin@hadassah.org.il |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Transluminal, Percutaneous Coronary
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adverse effects,
instrumentation* Animals Coronary Angiography Coronary Stenosis / therapy* Coronary Vessels / injuries* Male Materials Testing Models, Animal Pressure Safety Swine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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