| Effects of fluprazine hydrochloride on conspecific odor preferences in rats. | |
| | |
MedLine Citation:
|
PMID: 3737723 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The effect of Fluprazine Hydrochloride (DU 27716) on preference for conspecific male, estrous female and food odors was examined in male rats utilizing a two-compartment choice apparatus. Treatment with 8.0 mg/kg Fluprazine enhanced the preference of males for male odors but had no effect on preference for either estrous female or food odors. The drug-induced enhancement of male odor preference is consistent with the suggestion that Fluprazine interferes in some way with the processing of olfactory stimuli which normally precede offensive attack. The failure of the drug to alter the preference of males for estrous female odors suggests that the increased sniffing of estrous females noted during social testing may be secondary to other sources of conspecific stimulation or may reflect a highly transitory effect on olfactory processes. These results suggest that the suppressive effects of Fluprazine on intermale aggression and copulation are mediated by somewhat distinct mechanisms. |
| | |
Authors:
|
E D Kemble; L A Schultz; A E Thornton |
Related Documents
:
|
18207023 - Diet selection in immunologically manipulated mice. 2444073 - Capsaicin and its effects on olfaction and trigeminal chemoreception. 6729443 - Radioactivity in environmental samples taken in the sellafield and ravenglass areas of ... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Physiology & behavior Volume: 37 ISSN: 0031-9384 ISO Abbreviation: Physiol. Behav. Publication Date: 1986 |
Date Detail:
|
Created Date: 1986-09-17 Completed Date: 1986-09-17 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0151504 Medline TA: Physiol Behav Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 53-6 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Arousal / drug effects* Male Piperazines / pharmacology* Psychotropic Drugs / pharmacology* Rats Rats, Inbred Strains Sexual Behavior, Animal / drug effects Smell / drug effects* Social Behavior* Social Environment* |
| Chemical | |
Reg. No./Substance:
|
0/Piperazines; 0/Psychotropic Drugs; 76716-60-4/fluprazine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Failure of pimozide and metergoline to antagonize the RDS-127-induced facilitation of ejaculatory be...
Next Document: A reversible preparation for observing the behavior of fetal rats in utero: spinal anesthesia with l...