Document Detail


Effects of feeding diets contaminated with Fusarium mycotoxins on blood biochemical parameters of broiler chickens.
MedLine Citation:
PMID:  20713319     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
This study was conducted to investigate the effects of deoxynivalenol (DON) and zearalenone (ZEA) on some biochemical indices of broiler chickens. Twenty-four Ross 308 hybrid broiler chickens of both sexes were fed diets containing maize contaminated with Fusarium mycotoxins. The diets included a control diet (DON 0.60 mg/kg feed; ZEA 0.07 mg/kg feed), an experimental 1 diet (DON 3.4 mg kg⁻¹ feed; ZEA 3.4 mg kg⁻¹ feed), and an experimental 2 diet (DON 8.2 mg kg⁻¹ feed; ZEA 8.3 mg kg⁻¹ feed). Contaminated diets were fed from 14 days of age for 14 days. Blood samples were collected from 4-week-old birds. Chicks fed a diet containing a low level of contaminated maize (experimental 1) had decreased plasma potassium, magnesium, phosphorus, total protein, albumin, triglycerides, free glycerol concentrations and increased cholesterol and calcium levels as well as alkaline phosphatase (ALP) and aspartate aminotransferase (AST) enzyme activities as compared to the control. Feeding a diet contaminated with high levels of mycotoxins (experimental 2) resulted in decreased plasma potassium, magnesium, total protein, albumin, triglycerides, free glycerol concentrations and increased plasma ALP, alanine aminotransferase (ALT) and AST enzyme activities. The effect of mycotoxin-contaminated diets on ALP activity was dose dependent. Chloride concentration was not affected by the diets. It can be concluded that feeding diets contaminated with both levels of Fusarium mycotoxins significantly affected protein, lipid and mineral metabolism as well as AST and ALP enzyme activities in broiler chickens.
Authors:
Zita Faixová; Stefan Faix; Radka Borutová; Lubomír Leng
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta veterinaria Hungarica     Volume:  58     ISSN:  0236-6290     ISO Abbreviation:  Acta Vet. Hung.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8406376     Medline TA:  Acta Vet Hung     Country:  Hungary    
Other Details:
Languages:  eng     Pagination:  275-85     Citation Subset:  IM    
Affiliation:
University of Veterinary Medicine, Komenského 73, 04181 Kosice, Slovak Republic. faixova@uvm.sk
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