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THE EFFECTS OF EXTRAPERIOSTEAL INJECTIONS OF BLOOD COMPONENTS ON PERIOSTEAL CELL PROLIFERATION.
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MedLine Citation:
PMID:  14228520     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Following extraperiosteal injections of saline, serum, or whole blood, the synthesis of DNA in the cells of the osteogenic layer of the femora of mice was stimulated to approximately two-thirds of the level obtained by fracture of the femora. Irrespective of the material injected, the proliferative response of the cells in the periosteum was similar. These studies have shown that neither bone fracture nor direct disruption of the periosteum is necessary to induce periosteal cell proliferation since a single extraperiosteal injection of physiological saline induces DNA synthesis.
Authors:
E A TONNA; E P CRONKITE
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of cell biology     Volume:  23     ISSN:  0021-9525     ISO Abbreviation:  J. Cell Biol.     Publication Date:  1964 Oct 
Date Detail:
Created Date:  1965-03-01     Completed Date:  1996-12-01     Revised Date:  2010-06-22    
Medline Journal Info:
Nlm Unique ID:  0375356     Medline TA:  J Cell Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  79-87     Citation Subset:  OM    
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MeSH Terms
Descriptor/Qualifier:
Blood*
Blood Cell Count*
Cell Division*
DNA*
Fractures, Bone*
Metabolism*
Mice*
Osteogenesis*
Periosteum*
Radiation Effects*
Research*
Sodium Chloride*
Chemical
Reg. No./Substance:
7647-14-5/Sodium Chloride; 9007-49-2/DNA
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): J Cell Biol
ISSN: 0021-9525
ISSN: 1540-8140
Publisher: The Rockefeller University Press
Article Information
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Copyright © 1964 by The Rockefeller Institute Press
Received Day: 13 Month: 12 Year: 1963
Print publication date: Day: 1 Month: 10 Year: 1964
Volume: 23 Issue: 1
First Page: 79 Last Page: 87
ID: 2106514
PubMed Id: 14228520

THE EFFECTS OF EXTRAPERIOSTEAL INJECTIONS OF BLOOD COMPONENTS ON PERIOSTEAL CELL PROLIFERATION
Edgar A. Tonna
Eugene P. Cronkite
From the Medical Research Center, Brookhaven National Laboratory, Upton, New York


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