| Effects of extradural anaesthesia on human fetal blood flow in utero. Comparison of three local anaesthetic solutions. | |
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MedLine Citation:
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PMID: 3676055 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty-seven women, scheduled for elective Caesarean section under extradural anaesthesia were allocated randomly to one of three groups: group Ea received 1.5% etidocaine with adrenaline, group Bp 0.5% bupivacaine plain, and group Ba 0.5% bupivacaine with adrenaline. There was no difference in the quality and distribution of sensory blockade between the three groups. Motor blockade was most profound in group Ea. Maternal heart rate and arterial pressure were only slightly affected in the three groups. Before induction of extradural anaesthesia, and 15 and 30 min after, fetal umbilical and aortic blood flows were examined using a combination of real-time ultrasonography and the pulsed Doppler technique. Blood flow in the umbilical vein was not affected in any of the groups, and blood flow in the fetal aorta remained unchanged in groups Ea and Bp, but was increased by 12% after 30 min in group Ba. We conclude that, with the three local anaesthetic solutions studied during extradural anaesthesia for elective Caesarean section, fetal circulatory variables remained stable and within normal limits, when in association with normal values of maternal arterial pressure. |
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Authors:
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A Lindblad; J Bernow; E Vernersson; K Marsál |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: British journal of anaesthesia Volume: 59 ISSN: 0007-0912 ISO Abbreviation: Br J Anaesth Publication Date: 1987 Oct |
Date Detail:
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Created Date: 1987-12-30 Completed Date: 1987-12-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372541 Medline TA: Br J Anaesth Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1265-72 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Malmo General Hospital, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anesthesia, Epidural* Anesthesia, Obstetrical* Blood Circulation / drug effects* Bupivacaine / pharmacology Cesarean Section Epinephrine / pharmacology Etidocaine / pharmacology Female Fetus / physiology* Heart Rate, Fetal / drug effects Humans Infant, Newborn Pregnancy |
| Chemical | |
Reg. No./Substance:
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2180-92-9/Bupivacaine; 36637-18-0/Etidocaine; 51-43-4/Epinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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