| Effects of exercise, vitamin E, and ozone on pulmonary function and lipid peroxidation. | |
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MedLine Citation:
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PMID: 730598 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Expired pentane, an index of lipid peroxidation, and pulmonary function were measured as a function of exercise for 1 h with and without exposure to 0.3 ppm ozone. In experiment 1, 10 subjects who exercised on a bicycle ergometer at 50% of maximal oxygen consumption while being exposed to 0.3 ppm ozone had increased lung residual volume and decreased vital capacity, maximal midexpiratory flow rate, and forced expiratory volume in 1 s. In experiment 2, breath collected into a spirometer filled with hydrocarbon-scrubbed air showed increased pentane from the stress of exercise but no effect of ozone. During rest and exercise in experiment 3, two of six subjects had higher pentane levels than the other subjects. Following daily supplementation with 1,200 IU dl-alpha-tocopherol for 2 wk, the mean production of pentane during rest and exercise was significantly lowered, and there was no difference in pentane production among the subjects. It was concluded that lipid peroxidation occurs during exercise and that it is attenuated by vitamin E. |
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Authors:
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C J Dillard; R E Litov; W M Savin; E E Dumelin; A L Tappel |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of applied physiology: respiratory, environmental and exercise physiology Volume: 45 ISSN: 0161-7567 ISO Abbreviation: J Appl Physiol Publication Date: 1978 Dec |
Date Detail:
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Created Date: 1979-03-24 Completed Date: 1979-03-24 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 7801242 Medline TA: J Appl Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 927-32 Citation Subset: IM; S |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Humans Lung / physiology* Male Oxygen Consumption Ozone / pharmacology* Pentanes* Physical Exertion* Residual Volume Respiration* Vital Capacity Vitamin E / pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Pentanes; 10028-15-6/Ozone; 1406-18-4/Vitamin E |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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