Document Detail

Effects of exercise training on heart-rate-variability indices in individuals with Down Syndrome.
MedLine Citation:
PMID:  20543218     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To investigate the effects of an exercise-training program on heart-rate-variability (HRV) indices in individuals with Down syndrome (DS). DESIGN: Controlled clinical trial. PARTICIPANTS: 10 people with DS, age 24.2 +/- 5.1 y (group A), and 10 age-matched healthy sedentary individuals (group B). METHOD: At baseline all subjects underwent a clinical examination and an ambulatory 24-h Holter monitoring for the evaluation of cardiac autonomic-nervous-system (ANS) activity by time- and frequency-domain analysis. INTERVENTION: After initial evaluation, group A followed a 6-mo exercise-training program and thereafter underwent the same HRV analysis. RESULTS: At the beginning of the study, group A showed a higher LF:HF ratio than group B, indicating impaired sympathovagal balance, likely because of lesser vagal modulation. Moreover, both time- and frequency-domain indices in group A were significantly lower than in group B. At the end of the study, exercise training was found to improve the sympathovagal balance, mainly by increasing vagal activity, in group A. CONCLUSION: The results indicate that individuals with DS have ANS dysfunction that can be improved by exercise's increasing the parasympathetic modulation.
Fani Giagkoudaki; Eleftherios Dimitros; Evangelia Kouidi; Asterios Deligiannis
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of sport rehabilitation     Volume:  19     ISSN:  1056-6716     ISO Abbreviation:  J Sport Rehabil     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-06-14     Completed Date:  2010-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9206500     Medline TA:  J Sport Rehabil     Country:  United States    
Other Details:
Languages:  eng     Pagination:  173-83     Citation Subset:  IM    
Dept of Physical Education and Sports Science, Aristotle University of Thessaloniki, Thessaloniki, Greece.
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MeSH Terms
Autonomic Nervous System / physiopathology
Case-Control Studies
Down Syndrome / physiopathology*,  therapy
Electrocardiography, Ambulatory
Exercise Therapy*
Heart Rate*
Sedentary Lifestyle
Statistics, Nonparametric
Time Factors
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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