Document Detail

Effects of exercise training on heart rate recovery in patients with chronic heart failure.
MedLine Citation:
PMID:  17540210     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Heart rate recovery (HRR) is a marker of vagal tone that is associated with survival, but little is known about the effects of exercise training on HRR in patients with heart failure (HF). METHODS: Twenty-four patients with HF were randomized to a 2-month residential rehabilitation program or to usual care. Symptom-limited exercise testing was performed at baseline and at discharge from the program. Heart rate recovery was expressed as the decline in heart rate from peak exercise through 6 minutes into recovery. In addition, HRR recovery curves were normalized to a range of 1 at peak heart rate and 0 at 6 minutes and adjusted for differences in heart rate reserve, facilitating the comparison of recovery curve shapes between groups. RESULTS: Mean peak oxygen uptake and oxygen uptake at the lactate threshold increased 26% (P < .05) and 39% (P < .001), respectively, in the exercise group, whereas neither of these responses changed significantly among controls. Heart rate recovery was significantly more rapid in the exercise group after training (main effect 12.6 vs 2.6 beat/min in the trained and control groups, respectively, P = .005). The normalized curves showed that the largest improvement in recovery curve shape occurred in the exercise group, but most of the HRR improvement was accounted for by a widening of the difference between peak and resting heart rate. CONCLUSION: Exercise training results in a faster HRR in patients with HF. Heart rate recovery, as a simple marker of autonomic function, is an easily acquired response that may be useful for evaluating patient outcomes in cardiac rehabilitation.
Jonathan Myers; David Hadley; Ulrike Oswald; Karin Bruner; Wilhard Kottman; Leon Hsu; Paul Dubach
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American heart journal     Volume:  153     ISSN:  1097-6744     ISO Abbreviation:  Am. Heart J.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-06-01     Completed Date:  2007-06-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1056-63     Citation Subset:  AIM; IM    
Rehabilitation Center, Seewis, Switzerland.
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MeSH Terms
Analysis of Variance
Chronic Disease
Exercise Test
Exercise Therapy*
Heart Failure / physiopathology*,  rehabilitation*
Heart Rate
Middle Aged
Oxygen / pharmacokinetics
Pulmonary Gas Exchange
Reg. No./Substance:

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