Document Detail

Effects of exercise training on heart rate and QT interval in healthy young individuals: are there gender differences?
MedLine Citation:
PMID:  17224424     Owner:  NLM     Status:  MEDLINE    
AIMS: The aim of the present study was to assess the effects of exercise training on heart rate, QT interval, and on the relation between ventricular repolarization and heart rate in men and women. METHODS AND RESULTS: A 24 h Holter recording was obtained in 80 healthy subjects (40 males) who differed for the degree of physical activity. Trained individuals showed a lower heart rate and a higher heart rate variability than sedentary subjects, independent of the gender difference in basal heart rate. Mean 24 h QTc was similar in trained and non-trained men, while a significant difference was observed between trained and non-trained women. Exercise training reduced the QT/RR slope in both genders. This effect on the QT/RR relation was more marked in women; in fact, the gender difference in the ventricular repolarization duration at low heart rate observed in sedentary subjects was no longer present among trained individuals. CONCLUSION: The results of this study suggest that the cardiovascular response to exercise training may be different in men and women. Women may benefit more from interventions aimed to increase physical activity as a tool for prevention of cardiovascular morbidity and mortality.
Simonetta Genovesi; Daniele Zaccaria; Emanuela Rossi; Maria Grazia Valsecchi; Andrea Stella; Marco Stramba-Badiale
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article    
Journal Detail:
Title:  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology     Volume:  9     ISSN:  1099-5129     ISO Abbreviation:  Europace     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-01-16     Completed Date:  2007-03-15     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  100883649     Medline TA:  Europace     Country:  England    
Other Details:
Languages:  eng     Pagination:  55-60     Citation Subset:  IM    
Dipartimento di Medicina Clinica Prevenzione e Biotecnologie, University of Milano-Bicocca, Sanitarie, Via Cadore 48, 20052-Monza, Italy.
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MeSH Terms
Exercise / physiology*
Heart Rate / physiology*
Rest / physiology
Sex Characteristics*
Ventricular Function

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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