Document Detail

Effects of exercise training and exhaustion on 45Ca uptake by rat skeletal muscle mitochondria and sarcoplasmic reticulum.
MedLine Citation:
PMID:  134437     Owner:  NLM     Status:  MEDLINE    
Mitochondrial and sarcoplasmic reticular 45Ca2+ uptake and Ca2+-ATPase activity were determined in skeletal muscle from exercise trained and non-trained rats at rest or following short-term exhaustive exercise. In trained rats exercised to exhaustion, mitochondrial 45Ca2+ uptake was significantly depressed when compared to non-trained rats at rest. Ca2+-ATPase activity of sarcoplasmic reticulum from trained rats exercised to exhaustion was significantly increased as compared to trained rats at rest. These data suggest that the disruptive influence of Ca2+ accumulation in mitochondria isolated following exhaustive exercise may be diminished as a result of training.
H W Bonner; S W Leslie; A B Combs; C A Tate
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Research communications in chemical pathology and pharmacology     Volume:  14     ISSN:  0034-5164     ISO Abbreviation:  Res. Commun. Chem. Pathol. Pharmacol.     Publication Date:  1976 Aug 
Date Detail:
Created Date:  1976-11-01     Completed Date:  1976-11-01     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0244734     Medline TA:  Res Commun Chem Pathol Pharmacol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  767-70     Citation Subset:  IM; S    
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MeSH Terms
Adenosine Triphosphatases / metabolism
Adenosine Triphosphate / metabolism
Calcium / metabolism*
Calcium Radioisotopes
Mitochondria, Muscle / enzymology,  metabolism*
Muscles / ultrastructure*
Physical Exertion*
Sarcoplasmic Reticulum / enzymology,  metabolism*
Reg. No./Substance:
0/Calcium Radioisotopes; 56-65-5/Adenosine Triphosphate; 7440-70-2/Calcium; EC 3.6.1.-/Adenosine Triphosphatases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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