Document Detail

Effects of exercise training on abdominal obesity and related metabolic complications.
MedLine Citation:
PMID:  8776009     Owner:  NLM     Status:  MEDLINE    
Excessive deposition of visceral adipose tissue is known to predispose to cardiovascular diseases. Considerable epidemiological and experimental evidence suggests that many physiological factors are involved in the aetiology of premature atherosclerosis associated with visceral obesity. Insulin resistance is frequently associated with abdominal obesity, and probably plays an important role in the pathophysiology of hypertriglyceridaemia, low levels of plasma high-density lipoprotein (HDL)-cholesterol, hypertension and reduced fibrinolytic activity. Exercise training may counteract the aberrant metabolic profile associated with abdominal obesity both directly and as a consequence of body fat loss. Exercise may increase insulin sensitivity, favourably alter the plasma lipoprotein profile and improve fibrinolytic activity. Changes in the activity of insulin-sensitive glucose transporters and of skeletal muscle lipoprotein lipase are some of the possible explanations for the increased insulin sensitivity and improved blood lipid profile associated with regular exercise. This review presents physical training as a relevant nonpharmacological tool in the treatment of abdominal obesity and associated metabolic disorders. The impact of regular exercise on the different aspects of the insulin resistance syndrome is discussed. The roles of gender, age and the state of insulin resistance on the metabolic effect of physical training are also considered.
B Buemann; A Tremblay
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Sports medicine (Auckland, N.Z.)     Volume:  21     ISSN:  0112-1642     ISO Abbreviation:  Sports Med     Publication Date:  1996 Mar 
Date Detail:
Created Date:  1996-11-21     Completed Date:  1996-11-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8412297     Medline TA:  Sports Med     Country:  NEW ZEALAND    
Other Details:
Languages:  eng     Pagination:  191-212     Citation Subset:  IM; S    
Physical Activity Sciences Laboratory, PEPS, Laval University, Ste-Foy, Quebec, Canada.
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MeSH Terms
Cardiovascular Diseases / physiopathology
Cholesterol / blood
Diabetes Mellitus, Type 2 / physiopathology
Exercise / physiology*
Insulin Resistance
Muscle, Skeletal / physiology
Myocardial Infarction / physiopathology
Obesity / blood,  physiopathology*
Reg. No./Substance:

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