| Effects of exercise on natriuretic peptides and cardiac function in man. | |
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MedLine Citation:
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PMID: 9740477 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We evaluated cardiac function and the plasma levels of atrial (ANP) and brain (BNP) natriuretic peptides during bicycle (B) and hand-grip (HG) exercises in eight healthy males. Each test was preceded by a control protocol in resting conditions. Left ventricular (LV) function (echocardiography) was evaluated during both exercises. Atrial function was assessed only during HG. Plasma ANP significantly increased during B (+236%) and HG (+77%), while there was a significant trend towards higher plasma BNP levels during B (+41%) and HG (+30%) than during the corresponding control tests. Plasma ANP correlated with heart rate in both tests, with left atrial volume, pulmonary vein flow systolic fraction and mitral flow E/A ratio in HG; BNP in both test correlated with LV dimensions and function. These data suggest that during exercise the cardiac release of ANP and BNP is differently regulated and related to changes in left atrial and LV function, respectively. |
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Authors:
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G Barletta; L Stefani; R Del Bene; C Fronzaroli; S Vecchiarino; C Lazzeri; F Fantini; G La Villa |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal of cardiology Volume: 65 ISSN: 0167-5273 ISO Abbreviation: Int. J. Cardiol. Publication Date: 1998 Aug |
Date Detail:
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Created Date: 1999-02-16 Completed Date: 1999-02-16 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: IRELAND |
Other Details:
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Languages: eng Pagination: 217-25 Citation Subset: IM |
Affiliation:
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Istituto di Medicina Interna, University of Florence School of Medicine, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Analysis of Variance Atrial Function / physiology Atrial Natriuretic Factor / blood* Echocardiography Exercise / physiology* Exercise Test Hand Strength / physiology Heart / physiology* Hemodynamics / physiology Humans Linear Models Male Natriuretic Peptide, Brain / blood* Ventricular Function, Left / physiology |
| Chemical | |
Reg. No./Substance:
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114471-18-0/Natriuretic Peptide, Brain; 85637-73-6/Atrial Natriuretic Factor |
| Comments/Corrections | |
Comment In:
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Int J Cardiol. 1998 Nov 30;67(1):87
[PMID:
9880205
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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