| Effects of exercise intensity on lymphocyte H2O2 production and antioxidant defences in soccer players. | |
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MedLine Citation:
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PMID: 18070804 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Physical exercise is capable of enhancing or suppressing the immune response depending on the intensity and duration of exercise. This study investigated how exercise intensity influences the lymphocyte antioxidant response and the induction of cellular oxidative damage. DESIGN: Eighteen voluntary male pre-professional soccer players participated in this study. Sportsmen played a 60 min training match, and were divided into three groups depending on the intensity degree during the match: low, medium and high intensities. Measurements: Malondialdehyde (MDA), vitamins C and E and haem oxygenase-1 (HO-1) gene expression were measured in lymphocytes. Reactive oxygen species (ROS) production was determined in lymphocytes and neutrophils. RESULTS: Lymphocyte MDA levels and H(2)O(2) production were significantly increased in the group which performed the most intense exercise. Neutrophil counts and ROS production increased progressively with the exercise intensity. Vitamin C significantly decreased after exercise in the highest-intensity group in comparison with initial values, whereas vitamin E levels significantly increased in the medium and high-intensity groups. HO-1 gene expression significantly increased in the medium and high-intensity groups. CONCLUSIONS: Exercise intensity affects the lymphocyte and neutrophil oxidant/antioxidant balance, but only exercise of high intensity induces lymphocyte oxidative damage. |
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Authors:
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A Sureda; M D Ferrer; P Tauler; D Romaguera; F Drobnic; P Pujol; J A Tur; A Pons |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2007-12-10 |
Journal Detail:
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Title: British journal of sports medicine Volume: 43 ISSN: 1473-0480 ISO Abbreviation: Br J Sports Med Publication Date: 2009 Mar |
Date Detail:
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Created Date: 2009-03-09 Completed Date: 2009-11-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0432520 Medline TA: Br J Sports Med Country: England |
Other Details:
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Languages: eng Pagination: 186-90 Citation Subset: IM |
Affiliation:
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Laboratori de Ciències de l'Activitat Física, Departamentde Biologia Fonamental i Ciències de la Salut, Universitatde les Illes Balears, Spain. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Analysis of Variance Antioxidants / metabolism* Ascorbic Acid / metabolism Exercise / physiology* Humans Hydrogen Peroxide / metabolism* Lymphocytes / metabolism* Male Malondialdehyde / metabolism Reactive Oxygen Species / metabolism Reverse Transcriptase Polymerase Chain Reaction Soccer / physiology* Vitamin E / metabolism Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Reactive Oxygen Species; 1406-18-4/Vitamin E; 50-81-7/Ascorbic Acid; 542-78-9/Malondialdehyde; 7722-84-1/Hydrogen Peroxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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