| Effects of exercise on endothelium and endothelium/smooth muscle crosstalk: Role of exercise-induced hemodynamics. | |
| | |
MedLine Citation:
|
PMID: 21436465 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Physical activity, exercise training and fitness are associated with decreased cardiovascular risk. In the context that a risk factor "gap" exists in the explanation for the beneficial effects of exercise on cardiovascular disease, it has recently been proposed that exercise generates hemodynamic stimuli which exert direct effects on the vasculature which are anti-atherogenic. In this review we briefly introduce some of the in vitro and in vivo evidence relating exercise hemodynamic modulation and vascular adaptation. In vitro data clearly demonstrates the importance of shear stress as a potential mechanism underlying vascular adaptations associated with exercise. Supporting this is in vivo human data demonstrating that exercise-mediated shear stress induces localised impacts on arterial function and diameter. Emerging evidence suggests that exercise-related changes in hemodynamic stimuli other than shear stress may also be associated with arterial remodeling. Taken together, in vitro and in vivo data strongly imply that hemodynamic influences combine to orchestrate a response to exercise and training which regulates wall stress, peripheral vascular resistance and contributes to the anti-atherogenic impacts of physical activity, fitness and training. |
| | |
Authors:
|
Sean C Newcomer; Dick H J Thijssen; Daniel John Green |
Related Documents
:
|
11428685 - Physiological and performance characteristics of male professional road cyclists. 11217015 - Effects of external loading on power output in a squat jump on a force platform: a comp... 19057405 - Optimal frequency, displacement, duration, and recovery patterns to maximize power outp... 7872005 - Reduced oxygen availability during high intensity intermittent exercise impairs perform... 15229335 - Gastric bypass in a low-income, inner-city population: eating disturbances and weight l... 7716185 - Native speakers of spanish show rate-dependent processing of english stop consonants. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-3-24 |
Journal Detail:
|
Title: Journal of applied physiology (Bethesda, Md. : 1985) Volume: - ISSN: 1522-1601 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
|
Created Date: 2011-3-25 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8502536 Medline TA: J Appl Physiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
1Purdue University. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: LIGHT/ DARK OSCILLATIONS IN THE LUNG TRANSCRIPTOME: IMPLICATIONS FOR LUNG HOMEOSTASIS, REPAIR, METAB...
Next Document: Relationship between performance at different exercise intensities and skeletal muscle characteristi...