Document Detail


Effects of exercise conditioning on vital age in hyperlipidemic women.
MedLine Citation:
PMID:  11204875     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We attempted to determine the effectiveness of exercise prescription for women with hyperlipidemia (HL), because some HL women showed no significant improvement in serum lipid and lipoprotein profiles despite the continuation of exercise conditioning. We therefore tested the hypothesis that exercise can be clinically beneficial even when there are no alterations in total cholesterol (TC), low-density lipoprotein cholesterol (LDLC), and/or triglycerides (TG). Twenty-three women with HL (aged 54.3 +/- 7.6 yr) participated in our outpatient-supervised exercise conditioning program for 90 minutes each session, twice a week for 1 year, and also did home-based exercise three days a week. Vital age (VA) is a useful index for assessing functional status, especially the risk of coronary heart disease (CHD) and is computed from 11 independent variables measured not only when a person is at rest but also during exercise. Although TC and LDLC did not change significantly after the exercise conditioning, TG decreased significantly (P < 0.05). Furthermore, when we computed the corrected VA (VAc) assuming no changes in TC, LDLC, and TG, VAc was found to decrease significantly from 64.0 +/- 9.9 yr to 58.4 +/- 9.0 yr (P < 0.05). In conclusion, these results indicate the effectiveness of exercise conditioning on risk of CHD in HL women, irrespective of alterations in the concentrations of serum lipid and lipoprotein.
Authors:
R Shigematsu; K Tanaka; H Nho; M Nakagaichi; M Takeda; T Tomita; H Unno; S Ohkawa
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of physiological anthropology and applied human science     Volume:  19     ISSN:  1345-3475     ISO Abbreviation:  J Physiol Anthropol Appl Human Sci     Publication Date:  2000 Nov 
Date Detail:
Created Date:  2001-02-05     Completed Date:  2001-03-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100930389     Medline TA:  J Physiol Anthropol Appl Human Sci     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  279-85     Citation Subset:  IM    
Affiliation:
Institute of Health and Sport Sciences and Center for Tsukuba Advanced Research Alliance (TARA), University of Tsukuba. ryosuke@taiiku.tsukuba.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aging / physiology*
Cardiovascular Diseases / etiology,  prevention & control
Exercise Therapy*
Female
Health Status
Humans
Hyperlipidemias / complications,  therapy*
Middle Aged
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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