Document Detail


Effects of exercise at different times on postprandial lipemia and endothelial function.
MedLine Citation:
PMID:  18202576     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The purpose of this study was to examine the effects of previous exercise on metabolic, hormonal, and endothelial responses to an oral fat-tolerance test (OFTT). METHODS: Twelve healthy, recreationally trained men (age = 22.3 +/- 2.5 yr, weight = 80.7 +/- 12.4 kg, BMI = 25.1 +/- 3.1 kg.m(-2)) volunteered for this study. In a crossover fashion, subjects completed three OFTT trials that involved no exercise (NoEx) or exercise performed 16 h (EX-16) or 4 h (EX-4) before the ingestion of a meal (13 kcal.kg(-1) and 1.4 g of fat per kilogram of body weight). Blood was collected before and after the meal and hourly for 6 h. Brachial artery reactivity was measured using ultrasound before and at 2, 4, and 6 h after the meal. Dietary intake and exercise were standardized 4 d before the OFTT. The exercise session consisted of six resistance exercises and 30 min of running on a treadmill. The washout period between trials was, on average, 5 d. RESULTS: Compared with NoEx, there were significant (P < 0.05) decreases in triglyceride area under the curve (AUC) during EX-16 (-26%) and EX-4 (-15%). Compared with NoEx, there were decreases in insulin AUC during EX-16 (-7%, P < 0.05) and EX-4 (-5%, NS). EX-4 resulted in a significantly larger fasting arterial diameter than EX-16 and NoEx, but there were no other significant effects on endothelial function. Lipemic variables did not show correlations with endothelium function for any of the trials. CONCLUSION: An acute exercise session, regardless of the time point chosen (i.e., EX-16 or EX-4), reduced to a similar extent the total and incremental lipemic responses compared with the NoEx condition.
Authors:
Ricardo Silvestre; William J Kraemer; Erin E Quann; Richard L Seip; Carl M Maresh; Jakob L Vingren; Disa L Hatfield; Jeff S Volek
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Medicine and science in sports and exercise     Volume:  40     ISSN:  0195-9131     ISO Abbreviation:  Med Sci Sports Exerc     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-22     Completed Date:  2008-04-15     Revised Date:  2009-04-16    
Medline Journal Info:
Nlm Unique ID:  8005433     Medline TA:  Med Sci Sports Exerc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  264-74     Citation Subset:  IM; S    
Affiliation:
Human Performance Laboratory, Department of Kinesiology, University of Connecticut, Storrs, CT 06269, USA.
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Adult
Brachial Artery / physiology,  ultrasonography
Cardiovascular Diseases / prevention & control
Connecticut
Cross-Over Studies
Dietary Fats / administration & dosage
Endothelium / physiology*
Exercise / physiology*
Humans
Hyperlipidemias / blood,  metabolism*
Male
Postprandial Period / physiology*
Time Factors
Chemical
Reg. No./Substance:
0/Dietary Fats
Comments/Corrections
Comment In:
Med Sci Sports Exerc. 2008 Jul;40(7):1353; author reply 1354   [PMID:  18580417 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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