| Effects of estrogen on specific protein synthesis in the cockerel liver: an immunocytochemical study on major apoproteins in very low density and high density lipoproteins and albumin. | |
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MedLine Citation:
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PMID: 7379755 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of estrogen on two major apolipoproteins, apoVLDL-II and apoA-I, and albumin synthesis have been studied morphologically in cockerels using immunocytochemical methods. After the administration of a single dose of diethylstilbesterol (5 mg), the number of apoVLDL-II-containing hepatocytes increased markedly. The reaction product was also detected in the sinusoids. In contrast, the number of apoA-1- and albumin-containing cells did not seem to change significantly after estrogen treatment. The number of albumin-containing hepatocytes was higher than the number of apoVLDL II- or apoA-I-containing cells in the basal state. After estrogen, apoVLDL-II-containing cells were much more abundant than the other two cell types. The morphological changes induced by estrogen are correlated well with changes in the concentration of the three proteins in plasma after estrogen treatment. |
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Authors:
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C T Lin; L Chan |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Endocrinology Volume: 107 ISSN: 0013-7227 ISO Abbreviation: Endocrinology Publication Date: 1980 Jul |
Date Detail:
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Created Date: 1980-08-28 Completed Date: 1980-08-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0375040 Medline TA: Endocrinology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 70-5 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Apoproteins / biosynthesis* Chickens Diethylstilbestrol / pharmacology* Histocytochemistry Immunoassay Lipoproteins, HDL / biosynthesis* Lipoproteins, VLDL / biosynthesis* Liver / drug effects, metabolism* Male Serum Albumin / biosynthesis* |
| Chemical | |
Reg. No./Substance:
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0/Apoproteins; 0/Lipoproteins, HDL; 0/Lipoproteins, VLDL; 0/Serum Albumin; 56-53-1/Diethylstilbestrol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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