Document Detail


Effects of eradication therapy on gastric emptying in patients with Helicobacter pylori-positive duodenal ulcers.
MedLine Citation:
PMID:  11471854     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this study 28 patients with Helicobacter pylori-positive duodenal ulcers were treated with a 7-day triple-therapy regimen (omeprazole, clarithromycin, amoxycillin). Gastric emptying time was measured scintigraphically before and after therapy. Only 13 patients attended regularly for their endoscopic and scintigraphic follow-ups. Gastric emptying time was 57.6+/-16.5 min in 28 patients before therapy, and 44.4+/-13.9 min after therapy (44.7+/-7.9 min in the control group). The present study demonstrated gastric emptying time to be longer in the ulcer patients compared with healthy controls and that, after eradication therapy, gastric emptying time became almost normal in the ulcer patients.
Authors:
M D Onuk; H Uslu; E Varoğlu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of international medical research     Volume:  29     ISSN:  0300-0605     ISO Abbreviation:  J. Int. Med. Res.     Publication Date:    2001 May-Jun
Date Detail:
Created Date:  2001-07-26     Completed Date:  2001-12-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0346411     Medline TA:  J Int Med Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  178-80     Citation Subset:  IM    
Affiliation:
Gastroenterology Department, Atatürk University Medical Faculty, Erzurum, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Amoxicillin / administration & dosage,  pharmacology,  therapeutic use*
Clarithromycin / administration & dosage,  pharmacology,  therapeutic use*
Drug Therapy, Combination
Duodenal Ulcer / drug therapy*,  microbiology
Female
Gastric Emptying / drug effects*
Helicobacter pylori / isolation & purification*
Humans
Male
Middle Aged
Omeprazole / administration & dosage,  pharmacology,  therapeutic use*
Chemical
Reg. No./Substance:
26787-78-0/Amoxicillin; 73590-58-6/Omeprazole; 81103-11-9/Clarithromycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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