Document Detail


Effects of epilepsy on autonomic nervous system and respiratory function tests.
MedLine Citation:
PMID:  15256188     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have investigated autonomic nervous system function during the interictal period in epileptic patients and the possible effects of autonomic dysfunction on respiratory functions. A total of 32 epileptic patients (23 generalized, 9 partial epilepsy) and 32 healthy volunteers were involved. Sympathetic skin response (SSR), for evaluating the sympathetic nervous system, and RR interval variation (RRIV) were measured at the beginning and third month of antiepileptic treatment, and respiratory function tests (RFTs) were performed. In patients with partial epilepsy, SSR latency in the upper extremity (1.3+/-0.2 s) was longer than that of controls (1.2+/-0.3 s) at baseline (P=0.05), and was significantly reduced (1.1+/-0.3 s) after treatment (P<0.05). RRIV values of patients with generalized epilepsy were statistically significantly lower than those of controls (P<0.01). However, deep breathing RRIV values (32.6+/-15.3%) of patients were lower than those (43.0+/-18.2%) of controls (P<0.05). Sympathetic dysfunction was determined in patients with partial epilepsy and parasympathetic dysfunction in patients with generalized epilepsy. No abnormality was observed on RFTs for both patients with partial epilepsy and patients with generalized epilepsy.
Authors:
M Said Berilgen; Tacim Sari; Serpil Bulut; Bulent Mungen
Related Documents :
21511868 - Csf flow through the upper cervical spinal canal in chiari i malformation.
21273778 - The prevalence of long spinal cord lesions and anti-aquaporin 4 antibodies in neuromyel...
8250528 - Atrophy of mesial structures in patients with temporal lobe epilepsy: cause or conseque...
12143348 - Do recurrent seizures cause neuronal damage? a series of studies with mri volumetry in ...
3857648 - Evidence for physiological effects of hypercortisolemia in psychiatric patients.
20646358 - Functional infrared imaging of paroxysmal ischemic events in patients with raynaud's ph...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Epilepsy & behavior : E&B     Volume:  5     ISSN:  1525-5050     ISO Abbreviation:  Epilepsy Behav     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-07-16     Completed Date:  2004-09-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100892858     Medline TA:  Epilepsy Behav     Country:  United States    
Other Details:
Languages:  eng     Pagination:  513-6     Citation Subset:  IM    
Affiliation:
Department of Neurology, Faculty of Medicine, Firat University, Elazig, Turkey. msberilgen@yahoo.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Analysis of Variance
Autonomic Nervous System / drug effects,  physiopathology*
Case-Control Studies
Chi-Square Distribution
Epilepsy / drug therapy,  physiopathology*
Female
Galvanic Skin Response / physiology
Humans
Male
Reaction Time / drug effects
Respiration* / drug effects
Respiratory Function Tests / methods*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Lamotrigine for patients with juvenile myoclonic epilepsy following prior treatment with valproate: ...
Next Document:  Serum prolactin levels for differentiation of nonepileptic versus true seizures: limited utility.