Document Detail

Effects of elements in human blood pressure control.
MedLine Citation:
PMID:  11934245     Owner:  NLM     Status:  MEDLINE    
This review enumerates and discusses the elements involved in the control of human blood pressure via a historical evolutionary form. The older and most recent element literature presentations were researched using MEDLINE and a manual review of documents cited. Independent data extraction and cross-referencing was performed. Of the 28 known elements that can influence blood pressure, 15 were found to be involved in human blood pressure regulation. The elements were divided into four groups: electrolyte, composed of sodium, potassium, calcium, and magnesium; metal, which included zinc, copper, and iron; toxic, made up of lead, mercury, cadmium, barium, thallium, arsenic; miscellaneous (lithium and selenium). Evolutionary historical data, possible mechanisms of actions, and interactions between elements that have been shown to influence blood pressure are discussed. Controversy exists over the therapeutic use of elements to alter blood pressure but is absent in the case of the toxic group where preventive control is a proven public health matter. The significance of these 15 elements in the regulation of human blood pressure has been established and ongoing studies will continue to reinforce their influence and importance.
Hubert F Loyke
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Biological trace element research     Volume:  85     ISSN:  0163-4984     ISO Abbreviation:  Biol Trace Elem Res     Publication Date:  2002 Mar 
Date Detail:
Created Date:  2002-04-05     Completed Date:  2002-09-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7911509     Medline TA:  Biol Trace Elem Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  193-209     Citation Subset:  IM    
St. Vincent Charity Hospital, Department of Medicine, Cleveland, OH 44115, USA.
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MeSH Terms
Blood Pressure / drug effects*
Electrolytes / pharmacology*
Lithium / pharmacology
Metals / pharmacology*
Selenium / pharmacology
Trace Elements / pharmacology*
Reg. No./Substance:
0/Electrolytes; 0/Metals; 0/Trace Elements; 7439-93-2/Lithium; 7782-49-2/Selenium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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