Document Detail

Effects of electroacupuncture at different points on colorectal distention-induced changes in blood pressure, electrogastrogram, gastric tension and gastric blood flow.
MedLine Citation:
PMID:  22462246     Owner:  NLM     Status:  In-Process    
OBJECTIVE: To investigate the specificity of the effects of electroacupuncture (EA) at different acupoints on gastric functional activity and gastric blood flow after colorectal distension (CRD) in the rat.
METHODS: Fifty Wistar rats were randomly divided into 5 groups: a control group, a Zusanli group, a non-point group, a Taichong group and a Neiguan group. Rats were anesthetized after 18 h of fasting, and a rat model of nociceptive blood pressure elevation and abnormal electrogastrogram (EGG) and gastric tension (GT) was prepared by gasbag-induced CRD. EA was given bilaterally, and its effects on gastric blood flow (GBF) of the arcus vasculosi of the greater omentum, blood pressure, EGG fast wave properties, and gastric smooth muscle tension (GT) were quantified.
RESULTS: CRD induced an increase in blood pressure that was significantly inhibited by EA at all points (all P < 0.05), and the inhibitory effects were greater in the Zusanli and Neiguan groups compared to the non-point group (both P < 0.05). CRD also caused reductions in GT and GBF, and in the amplitude, frequency and duration of EGG waves (all P < 0.05). These effects were also reversed by EA. The effects of EA on EGG wave amplitude, GT, and GBF were superior in the Zusanli group compared to the Taichong group, Neiguan group, and the non-point group.
CONCLUSION: EA significantly counteracted CRD-induced changes in blood pressure, GBF, EGG, and GT. The effects of stimulation at Zusanli (ST 36) were significantly greater compared to other points, indicating relative specificity of this acupoint.
Shu-Ping Chen; Yong-Hui Gao; Jun-Ying Wang; Jun-Ling Liu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan / sponsored by All-China Association of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine     Volume:  31     ISSN:  0255-2922     ISO Abbreviation:  J Tradit Chin Med     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2012-04-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211546     Medline TA:  J Tradit Chin Med     Country:  China    
Other Details:
Languages:  eng     Pagination:  360-6     Citation Subset:  IM    
China Academy of Chinese Medical Sciences, Beijing 100700, China.
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