Document Detail


Effects of diffuse fatty infiltration of the liver on portal vein flow hemodynamics.
MedLine Citation:
PMID:  18196595     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To investigate the effects of various degrees of diffuse fatty infiltration of the liver on portal vein blood flow with Doppler sonography. METHODS: One hundred forty subjects were examined with color and spectral Doppler sonography. The subjects were divided into 4 groups of 35 subjects each according to the degree (normal, grade 1, grade 2 and grade 3) of hepatic fatty infiltration assessed on gray-scale images. The portal vein pulsatility index (VPI) and time-averaged mean flow velocity (MFV) were calculated for each subject. VPI was calculated as (peak maximum velocity - peak minimum velocity) / peak maximum velocity. RESULTS: VPI and MFV values were, respectively, 0.32 +/- 0.06 and 16.8 +/- 2.6 cm/second in the normal group, 0.27 +/- 0.07 and 14.2 +/- 2.2 cm/second in the group with grade 1 fatty infiltration, 0.22 +/- 0.06 and 12.2 +/- 1.8 cm/second in the group with grade 2 fatty infiltration, and 0.18 +/- 0.04 and 10.8 +/- 1.5 cm/second in the group with grade 3 fatty infiltration. There was a negative inverse correlation between the grade of fatty infiltration and both VPI (f = 55.3, p < 0.001) and MFV (f = 43.9, p < 0.001). CONCLUSION: The pulsatility index and mean velocity of the portal vein blood flow decrease as the severity of fatty infiltration increases.
Authors:
Ali Balci; Sinem Karazincir; Haldun Sumbas; Yasemin Oter; Ertugrul Egilmez; Tacettin Inandi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical ultrasound : JCU     Volume:  36     ISSN:  0091-2751     ISO Abbreviation:  J Clin Ultrasound     Publication Date:    2008 Mar-Apr
Date Detail:
Created Date:  2008-03-10     Completed Date:  2008-07-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401663     Medline TA:  J Clin Ultrasound     Country:  United States    
Other Details:
Languages:  eng     Pagination:  134-40     Citation Subset:  IM    
Copyright Information:
(Copyright) 2007 Wiley Periodicals, Inc.
Affiliation:
Department of Radiology, Mustafa Kemal University Faculty of Medicine, Bağriyanik Mh. Uğur Mumcu Cad., 31100 Antakya, Hatay, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Flow Velocity
Fatty Liver / complications*,  physiopathology*
Female
Hemodynamics*
Humans
Liver / blood supply,  physiopathology*,  ultrasonography
Male
Middle Aged
Portal Vein / physiopathology*,  ultrasonography
Prospective Studies
Severity of Illness Index
Ultrasonography, Doppler, Color

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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